The efficiency of obesity treatment in patients with insomnia and obstructive sleep apnea syndrome
https://doi.org/10.14341/omet2016225-32
Abstract
The aim of this study was to investigate the relationship between the dynamics of body weight and sleep disorders in the treatment of obesity.
Materials and methods. The study included 200 obese patients: 83 men and 117 women.
Results. Complaints about problems sleeping (snoring, hypersomnia, insomnia, etc.) were present in 78% of obese patients. 89 patients were under the observation of an endocrinologist for 7 ± 1 months, they were divided into three matched by age, sex and BMI groups: patients with obstructive sleep apnea syndrome (OSAS) (n = 42), the second – with the syndrome of insomnia (n = 19), the third (control group) – patients without sleep disorders (n = 24). After treatment of obesity the weight loss in patients with insomnia syndrome was -2.5 [-4; 0]kg, in patients with OSAS -7 [-18; -2] kg, in patients without sleep disorders -6.5 [-12; -2.25] kg. Clinically significant weight reduction was reached in 25 (59.5%) patients with OSAS; 3 (16%) – with insomnia syndrome; 15 (62.5%) – without sleep disorders.
Conclusion. Thus, the insomnia syndrome essentially influences the obesity treatment results – most of patients with this sleep disorder (81.2%) do not achieve clinically significant weight loss. The presence and severity of breathing disorders during sleep do not prevent weight loss. However, with the regular use of CPAP-therapy in patients with OSAS has a tendency of greater reduction of body weight.
About the Authors
Natal'ya V. Strueva
Endocrinology Research Centre
Russian Federation
MD, PhD
Competing Interests:
Russian Federation
MD, PhD
Competing Interests:
No conflict of interest
Galina A. Mel'nichenko
Endocrinology Research Centre
Russian Federation
MD, PhD, Professor
Competing Interests: No conflict of interest
Russian Federation
MD, PhD, Professor
Competing Interests: No conflict of interest
Mikhail G. Poluektov
I.M. Sechenov’s First Moscow State Medical University
Russian Federation
MD, PhD
Competing Interests: No conflict of interest
Russian Federation
MD, PhD
Competing Interests: No conflict of interest
Larisa V. Savel'eva
Endocrinology Research Centre
Russian Federation
MD, PhD
Competing Interests: No conflict of interest
Russian Federation
MD, PhD
Competing Interests: No conflict of interest
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Strueva N.V., Mel'nichenko G.A., Poluektov M.G., Savel'eva L.V. The efficiency of obesity treatment in patients with insomnia and obstructive sleep apnea syndrome. Obesity and metabolism. 2016;13(2):25-32. (In Russ.) https://doi.org/10.14341/omet2016225-32
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