The influence of orlistat (Xenical) therapy on the parameters of lipid metabolism in patients with obesity

doi:10.14341/2071-8713-5311

The influence of orlistat (Xenical) therapy on the parameters of lipid metabolism in patients with obesity

N Mazurina, N Masurina

https://doi.org/10.14341/2071-8713-5311

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Abstract

One of the main goals in treatment of obesity is descending of overall cardiometabolic risk, which is mostly defined by atherogenic changes in blood lipid spectrum. Scientific data, presented in this review confirm that orlistat is effective for treatment of obesity, its introduction significantly increases proportion of patients who reach clinically valuable results. The mechanism of action of orlistat explains its influence on parameters of blood lipids, which doesn't directly depend on the decrease of body mass during treatment. Improvement of cardiometabolic parameters during orlistsat treatment allows to consider this therapy as one of the methods for correction of dyslipidemia

Keywords

obesity, hyperlipidemia, orlistat, cholesterol

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For citations:

, The influence of orlistat (Xenical) therapy on the parameters of lipid metabolism in patients with obesity. Obesity and metabolism. 2009;6(2):7-11. (In Russ.) https://doi.org/10.14341/2071-8713-5311

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).

ISSN 2071-8713 (Print)
ISSN 2306-5524 (Online)

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Obesity and metabolism

The influence of orlistat (Xenical) therapy on the parameters of lipid metabolism in patients with obesity

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