Vitamin D the missing element in the treatment of obesity and diabetes?

Vitamin D supplementation has a significant positive effect on the skeletal system (prevention of rickets/osteomalacia; in severe deficiency, reduction in the risk of certain fractures and falls). However, for extraskeletal effects, which include acute respiratory infections, cardiovascular diseases, cancer, type 2 diabetes, and obesity, the data are mixed. Large randomized clinical trials in non-selected populations have generally failed to confirm a significant clinical benefit from vitamin D supplementation, while meta-analytic and subgroup data indicate a significant benefit in individuals with corrected baseline deficiency. Dosage regimen and baseline 25(OH)D status are key effect modifiers. Therefore, experts currently recommend a targeted approach screening and correcting deficiency and insufficiency in at-risk groups, achieving and maintaining target vitamin D levels. This literature review focuses on the effects of vitamin D supplementation in patients with obesity and carbohydrate metabolism disorders.

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59. Official instructions for the drug Soligamma®(In Russ.)