Obesity and metabolism

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ISSN 2306-5524 (Online)

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Obesity and cahexia as the first manifestations of craniopharingioma

https://doi.org/10.14341/omet2018143-49

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Abstract

The key structure in the regulation of energy homeostasis is the hypothalamus. The damage of the hypothalamic region can lead to imbalance of energy exchange with the development of obesity or cachexia. The most common metabolic disorders occur in case of craniopharyngiomas. The article presents two clinical observations of papillary craniopharyngioma in young women. Cases were accompanied by different disturbances of the energy balance, in one - with the development of obesity, in the other - cachexia.

Keywords

craniopharyngioma, diencephalic cachexia, diencephalic obesity, Russell's syndrome, hypothalamic tumor, hypopituitarism, diabetes insipidus

About the Authors

Liudmila I. Astafieva

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

Sc.D.

Irina S. Klochkova

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

Pavel L. Kalinin

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

Sc.D.

Boris A. Kadashev

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

Sc.D., Professor

Aleksandr N. Konovalov

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

Sc.D., prof., academician of RAS

Dmitrii V. Fomichev

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

PhD

Maksim A. Kutin

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

PhD

Oleg I. Sharipov

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

PhD

Ylia G. Sidneva

N.N. Burdenko National Medical Research Center of Neurosurgery

Russian Federation

PhD

Dina A. Yatsenko

FGBU RMANPO

Russian Federation

MD

Larisa K. Dzeranova

Endocrinology Research Centre

Russian Federation

Sc.D

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Supplementary files

	1. рисунки к статье ОЖИРЕНИЕ И КАХЕКСИЯ В КАЧЕСТВЕ ПЕРВЫХ ПРОЯВЛЕНИЙ ПАПИЛЛЯРНОЙ КРАНИОФАРИНГИОМЫ (описание двух клинических случаев).
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	2. Fig. 1. Appearance of the patient D. 36 years old.
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	3. Fig. 2. Appearance of the patient P. 24 years old
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	4. Fig. 3. MRI of patient D. 36 years old with contrast enhancement in T1 mode in sagittal (a) and frontal (b) projections prior to surgery.
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	5. Fig. 3. MRI of patient P. 24 years old with contrast enhancement in T1 mode in sagittal (in) and frontal (d) projections before surgery.
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Review

For citations:

Astafieva L.I., Klochkova I.S., Kalinin P.L., Kadashev B.A., Konovalov A.N., Fomichev D.V., Kutin M.A., Sharipov O.I., Sidneva Y.G., Yatsenko D.A., Dzeranova L.K. Obesity and cahexia as the first manifestations of craniopharingioma. Obesity and metabolism. 2018;15(1):43-49. (In Russ.) https://doi.org/10.14341/omet2018143-49

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ISSN 2071-8713 (Print)
ISSN 2306-5524 (Online)