Preview

Obesity and metabolism

Advanced search

The contribution of fat component to gestational weight gain

https://doi.org/10.14341/omet2013416-20

Abstract

Objective: to estimate the role of adipose tissue in gestational weight gain (GWG) and preferential fat deposition among normal-weight women. Subjects and methods: prospective cohort study of 84 pregnancies: maternal body mass index 18,5–24,9 kg/m2, singleton term pregnancy, nondiabetic women, somatically well. GWG and skinfold thickness were evaluated in the 1st, 2nd, 3d trimesters, on the 3d day after delivery. Results: fat mass gain in low GWG was similar to recommended GWG and in the high-GWG group was greater one. Women with recommended and low GWG returned to their initial fat level on the 3d day after delivery, in excessive weight gain fat significantly increased (р=0,025). Compared to initial recommended GWG resulted in triceps skinfold thicknesses loss (р=0,001), in abdominal skinfold gained nothing and in thighs skinfold thicknesses increasing (р=0,021). Inadequate GWG leads to fat loss in arms (р=0,017), fat of abdominal area and thighs return to initial level. In excessive GWG fat in the upper trunk and arms not changed, in the lower area (thighs) significantly increased compared to initial level (р=0,001) or other groups (р=0,001). Conclusion: excessive GWG was associated with greater adipose tissue cumulation and its deposition preferentially over the thighs. Inadequate GWG was clearly linked to low fat-free mass gain.

About the Authors

V Pokusaeva

dotsent kafedry akusherstva i ginekologii s kursom prenatal'noy diagnostiki


E Troshina

professor, zaveduyushchaya otdeleniem terapii s gruppoy metabolizma i ozhireniya


E Nikiforovskaya

tsent kafedry akusherstva i ginekologii s kursom prenatal'noy diagnostiki


A Vahrushina

aspirant kafedry akusherstva i ginekologii s kursom prenatal'noy diagnostiki


References

1. Герасимов А.Н. Медицинская статистика. Учебное пособие. М.: ООО «Медицинское информационное агентство», 2007; 480 с.

2. Нетребенко О.К. Метаболическое программирование в антенатальном периоде. Вопр. гин. акуш. и перинатол. 2012; 11 (6): 58–65.

3. Раджабова Ш.Ш., Омаров С.-М.А., Абусуев С.А.Течение и исход беременности у женщин с избыточной массой тела или ожирением. Рос. вестн. акуш.-гин. 2011; 6: 58–60.

4. Суплотова Л.А., Сметанина С.А., Новаковская Н.А. Распространенность ожирения, патологической прибавки массы тела и метаболического синдрома у женщин Крайнего Севера при беременности. Акуш гин. 2011; 2: 77–81.

5. Callaway L.K., McIntyre H.D., O’Callaghan M., Williams G M., Najman J.M., Lawlor D.A. The association of hypertensive disorders of pregnancy with weight gain over the subsequent 21 years: findings from a prospective cohort study. Am J Epid. 2007; 166(4): 421–428.

6. Chu S.Y., Callaghan W.M., Bish C.L., D’Angelo D. Gestational weight gain by body mass index among US women delivering live births, 2004–2005: Fueling future obesity. Am J Obst Gyn. 2009; 200. 271e1–271.e7.

7. Chung J.G., Taylor R.S., Thompson J.M., Anderson N.H., Dekker G.A., Kenny L.C., McCowan L.M. Gestational weight gain and adverse pregnancy outcomes in a nulliparous cohort. Eur J Obstet Gynecol Reprod Biol. 2013; 167(2): 149–53.

8. El-Chaar D., Finkelstein S.A., Tu X., Fell D.B., Gaudet L., Sylvain J., Tawagi G., Wen S.W., Walker M. The impact of increasing obesity class on obstetrical outcomes. J Obstet Gynaecol Can. 2013; 35(3): 224–33.

9. Gunderson E.P., B. Sternfeld M.F. Wellons R.A. Whitmer Chiang V., Quesenberry C.P., Jr., Lewis C.E., Sidney S. Childbearing may increase visceral adipose tissue independent of overall increase in body fat. Obesity (Silver Spring). 2008; 16(5): 1078–1084.

10. Higgins L., Mills T.A., Greenwood S.L., Cowley E.J., Sibley C.P., Jones R.L. Maternal obesity and its effect on placental cell turnover. J Matern Fetal Neonatal Med. 2013; 26(8):783–8.

11. Hilakivi-Clarke L., Luoto R., Huttunen T., Koskenvuo M. Pregnancy weight gain and premenopausal breast cancer risk. J Reprod Med. 2005; 50(11): 811–816.

12. Institute of Medicine (IOM). Weight gain during pregnancy: Reexamining the guidelines. Washington, DC. 2009: 857.

13. Jackson A.S., Pollock M.L., Ward A. Generalized equations for predicting body density of women. Medicine and Science in Sports and Exercise. 1980; 12: 175–182.

14. Kirwan J.P., Hauguel-De Mouzon S., Lepercq J., Challier J.C., Huston-Presley L., Friedman J. E., Kalhan S. C., Catalano P. M. TNF-alpha is a predictor of insulin resistance in human pregnancy. Diabetes. 2002; 51(7): 2207–2213.

15. Mission J.F., Marshall N.E., Caughey A.B. Obesity in pregnancy: a big problem and getting bigger. Obstet Gynecol Surv. 2013; 68(5): 389–99.

16. Risnes K.R., Vatten L.J., Baker J.L. Jameson K., Sovio U., Kajantie E., Osler M., Morley R., Jokela M., Painter R. C., Sundh V., Jacobsen G.W., Eriksson J. G., Sørensen T. I. A., Bracken M. B.Birthweight and mortality in adulthood: a systematic review and meta-analysis. Inter J Epid. 2011; 40: 647–661.

17. Ryan E. A., Enns L. Role of gestational hormones in the induction of insulin resistance. J of Clin Endocrin and Metabol. 1988; 67(2): 341–347.

18. Sohlstrom A., Forsum E. Changes in adipose tissue volume and distribution during reproduction in Swedish women as assessed by magnetic resonance imaging. Am J Clin Nutr. 1995; 61(2): 287–295.

19. Wrotniak B.H., Shults J., Butts S., Stettler N. Gestational weight gain and risk of overweight in the offspring at age 7 y in a multicenter, multiethnic cohort study. Am J Clin Nutr. 2008; 87(6): 1818–24.


Review

For citations:


 ,  ,  ,   The contribution of fat component to gestational weight gain. Obesity and metabolism. 2013;10(4):16-20. (In Russ.) https://doi.org/10.14341/omet2013416-20

Views: 637


ISSN 2071-8713 (Print)
ISSN 2306-5524 (Online)