Diabetes and consolidation of fractures
https://doi.org/10.14341/2071-8713-4819
Abstract
One of the complications of diabetes in humans is inadequate bone formation resulting in osteopenia and slow consolidation of fractures. The basis of these pathological processes is a disruption of the regeneration of bone tissue in insulin deficiency and hyperglycemia, the mechanisms of which are highlighted in this mini-review. The published data indicate the need for careful monitoring of blood glucose levels and adequate replacement therapy for the prevention of skeletal complications of diabetes.
Keywords
RANK/RANKL,
diabetes,
fractures,
osteoporosis,
RANK/RANKL,
osteoprotegerin,
vitamin D,
insulin,
hyperglycemia,
bone resorption
About the Authors
T Yalochkinavrach
E Pigarova
k.m.n., s.n.s. otdeleniya neyroendokrinologii i osteopatiy
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Review
For citations:
, Diabetes and consolidation of fractures. Obesity and metabolism. 2013;10(2):19-21. (In Russ.) https://doi.org/10.14341/2071-8713-4819
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