Evaluation of the lipid spectrum of blood in men under unfavorable working conditions in various climatic zones of the Krasnoyarsk Territory

BACKGROUND: Dyslipidemias occupy one of the leading places among modified risk factors for cardiovascular pathologies. 

AIM: Evaluation of the blood lipid spectrum in men under unfavorable working conditions in various climatic zones of the Krasnoyarsk Territory.

MATERIALS AND METHODS: Blood parameters were assessed in the Arctic (n=60), Subarctic (n=60), and temperate zones (n=60): triglycerides, total cholesterol, and highand low-density lipoproteins. Dyslipidemia types were determined: predominant triglyceridemia and hypercholesterolemia, mixed hyperlipidemia, and atherogenic hyperlipidemia. Age, total work experience, length of service in the North, nutritional status, and working conditions based on hazards were assessed. RESULTS: Conditions in the Arctic are of an organized team, in the Subarctic and temperate zone they are normal. Age is 35.7±3.4, 34.2±5.5 and 32.9±3.3 years without statistically significant differences, as well as the length of work experience: up to 40 years, 65.0%, 79.6% and 70.7%, respectively. Work experience in the North is 7.1±0.8 and 6.4±3.5 (p=0.450) years. The work is harmful: 3.3 (Arctic severity and intensity of work), 3.2 (Subarctic, temperate zone intensity of work). In the Arctic, hypercholesterolemia is in 43.1%, mixed in 41.2%, atherogenic dyslipidemia in 11.8%; In the Subarctic, hypercholesterolemia is found in 36.7%, mixed in 10.0%, atherogenic in 43.3%; in the temperate zone, hypercholesterolemia is found in 58.5%, mixed in 18.9%, atherogenic in 17.0%, and triglyceridemia in 1.9%.

CONCLUSION: Dyslipidemia is more pronounced with the combined effect of living conditions, low physical activity and intense mental work in the Subarctic. With mental work and physical exertion in the Arctic, the adaptive capabilities of the body are higher, which is confirmed by high high-density lipoproteins in 58.9%, as well as a smaller proportion of people with atherogenic dyslipidemia. The need to assess the lipid spectrum of the blood under unfavorable living and working conditions, regardless of age, and differentiated measures to prevent dyslipidemia has been established.

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