«Obesogenic memory» as a neurobiological mechanism predicting the recurrent course of obesity
https://doi.org/10.14341/omet13226
Abstract
Obesity is a significant healthcare problem worldwide. It is associated with a multitude of comorbidities and significantly reduces the quality of life. Success in the study of the pathogenesis of metabolic disorders contribute to development and introduction of innovative technologies into the clinical practice to combat the epidemic of obesity. However, so far the mechanisms involved in weight regain remain not fully understood. Maintaining body weight is regulated by the interaction of many physiological processes. The purpose of this review is to analyze existing studies dedicated to the biological mechanisms leading weight regain after successful treatment of obesity.
About the Authors
M. V. Shestakova
Endocrinology research centre
Russian Federation
Russian Federation
Christina E. Zakharova, resident
11 Dmitry Ulyanov street, 117292 Moscow
K. E. Zakharova
Endocrinology research centre
Russian Federation
Russian Federation
Marina V. Shestakova, MD, PhD, Professor
Moscow
Researcher ID: D-9123-2012
Scopus Author ID: 7004195530
I. M. Yurchenkova
Endocrinology research centre
Russian Federation
Russian Federation
Inna M. Yurchenkova, resident
Moscow
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1. Figure 1. The model for the role of weight changes in adipose tissue (adapted from the work of Van Baak MA at al., 2019) [30]. | |
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Shestakova M.V., Zakharova K.E., Yurchenkova I.M. «Obesogenic memory» as a neurobiological mechanism predicting the recurrent course of obesity. Obesity and metabolism. 2025;22(4):366-373. (In Russ.) https://doi.org/10.14341/omet13226
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