Obesity and infection. Another comorbidity?
https://doi.org/10.14341/omet9745
Abstract
A literature review is devoted to the problem of comorbidity of obesity (Ob) and infections. At present, extensive material has been accumulated about the increased propensity of patients with Ob to various infections (respiratory, urinary, viral, nosocomial, postoperative). One of the pathogenetic mechanisms of infection development in patients with Ob is dysfunction of cellular and humoral immunity, induced by adipose tissue production of cytokines (adipokines), which have an immunomodulating effect in various directions. Further research is needed in the field of epidemiology, mechanisms of development and course of infections in patients with Ob, as well as developing tactics for conducting this category of patients (diagnosis, antibiotic therapy, preoperative preparation, etc.).
About the Author
Leonid I. DvoretskiiI.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
MD, PhD, Professor, head of 2nd therapy department
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Dvoretskii L.I. Obesity and infection. Another comorbidity? Obesity and metabolism. 2019;16(2):3-8. (In Russ.) https://doi.org/10.14341/omet9745
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