Association between pathogenesis of atherosclerosis and osteoporosis
https://doi.org/10.14341/omet201648-14
Abstract
Currently, the leading place in the structure of morbidity in older people takes the cardiovascular disease. It is also the leading cause of death in developed countries. The significance of osteoporosis is now also due to the high and growing prevalence of this pathology. Osteoporotic fractures are associated with a reduction in the quality of life in patients, lead to disability, require a significant investment. This pathology is ranked fourth in the structure of mortality after cardiovascular disease, oncopathology, and diabetes.
Numerous studies indicate that these two diseases are associated not only with the occurrence of age, but have common pathogenetic mechanisms. The data obtained suggest that osteoporosis, calcification of the aorta and heart valves and atherosclerotic vascular disease – related pathological processes. Vascular and bone have some common morphological properties, vascular calcification and consists of the same components as the bone tissue.
From the standpoint of modern medicine it is extremely important to identify specific relationships between diseases and their common pathogenetic mechanisms for development of a comprehensive and individual approach to the diagnosis, treatment and prevention.
About the Authors
Andrey Verbovoy
Samara State Medical University
Russian Federation
ScD, prof.
Russian Federation
ScD, prof.
Ekaterina Mitroshina
Samara State Medical University
Russian Federation
PhD
Russian Federation
PhD
Anna Pashentseva
Samara State Medical University
Russian Federation
PhD
Russian Federation
PhD
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Verbovoy A., Mitroshina E., Pashentseva A. Association between pathogenesis of atherosclerosis and osteoporosis. Obesity and metabolism. 2016;13(4):8-14. (In Russ.) https://doi.org/10.14341/omet201648-14
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