Роль липотоксичности в патогенезе сахарного диабета 2 типа и ожирении
Аннотация
Ожирение является главным фактором риска развития сахарного диабета 2 типа (СД2), сердечно-сосудистых заболеваний и ассоциированных с ними коморбидных состояний. Традиционно считалось, что инсулинорезистентность определяется метаболизмом глюкозы. Однако в последние годы все больше и больше внимания уделяется обмену жирных кислот в организме, повышение уровня которых играет значительную роль в патофизиологических механизмах, связанных с инсулинорезистентностью.
Об авторах
F R AbdulkadirovaКафедра эндокринологии и диабетологии; ГБОУ ДПО РМАПО Минздрава России
A S Ametov
Кафедра эндокринологии и диабетологии; ГБОУ ДПО РМАПО Минздрава России
E V Doskina
Кафедра эндокринологии и диабетологии; ГБОУ ДПО РМАПО Минздрава России
R A Pokrovskaya
Кафедра эндокринологии и диабетологии; ГБОУ ДПО РМАПО Минздрава России
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Для цитирования:
Abdulkadirova F.R., Ametov A.S., Doskina E.V., Pokrovskaya R.A. Роль липотоксичности в патогенезе сахарного диабета 2 типа и ожирении. Ожирение и метаболизм. 2014;11(2):8-12. https://doi.org/10.14341/omet201428-12
For citation:
., ., ., . The role of the lipotoxicity in the pathogenesis of type 2 diabetes mellitus and obesity. Obesity and metabolism. 2014;11(2):8-12. (In Russ.) https://doi.org/10.14341/omet201428-12
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