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Ожирение и метаболизм

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Эффекты бариатрических операций на уровень гормонов, регулирующих массу тела. В чем основа успеха?

https://doi.org/10.14341/omet201443-11

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Аннотация

Растущая заболеваемость ожирением и сахарным диабетом 2 типа сделала бариатрическую хирургию широко распространенным методом лечения. Эффективность бариатрических операций в лечении ожирения и сопутствующих метаболических нарушений хорошо освещена в литературе. Тем не менее, результаты этих вмешательств не всегда коррелируют с типом операции. По-прежнему до конца не изучены механизмы влияния бариатрических вмешательств на инсулинорезистенность, энтеро-инсулярную ось, адипокины. Понимание этих механизмов позволит более точно определять показания к хирургическому лечению и повысить эффективность операции у конкретного пациента. Обзор посвящен влиянию различных типов бариатрических операций на уровень гормонов жировой ткани и желудочно-кишечного тракта, участвующих в регуляции аппетита, жирового и углеводного обмена. В статье рассмотрены современные представления о воздействии бариатрических вмешательств на метаболические нарушения при ожирение.

Об авторах

Алина Юрьевна Бабенко
ФГБУ "ФМИЦ им.В.А.Алмазова" ГБОУ ВПО "ПСПБГМУ им.акад.И.П.Павлова"
Россия
д.м.н., доцент кафедры


Александр Евгеньевич Неймарк
ФГБУ "ФМИЦ им.В.А.Алмазова" ГБОУ ВПО "ПСПБГМУ им.акад.И.П.Павлова"
Россия

к.м.н., ведущий научный сотрудник ФГБУ «ФМИЦ им.В.А. Алмазова».

Доцент кафедры факультетской хирургии ГБОУ ВПО ПСПбГМУ им. И.П. Павлова



Кристина Александровна Анисимова
ГБОУ ВПО "ПСПБГМУ им.акад.И.П.Павлова"
Россия
клинический ординатор


Елена Николаевна Гринева
ФГБУ "ФМИЦ им.В.А.Алмазова" ГБОУ ВПО "ПСПБГМУ им.акад.И.П.Павлова"
Россия

д.м.н., профессор, директор института эндокринологии ФГБУ
«ФМИЦ им. В.А. Алмазова»



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Дополнительные файлы

Для цитирования:


Бабенко А.Ю., Неймарк А.Е., Анисимова К.А., Гринева Е.Н. Эффекты бариатрических операций на уровень гормонов, регулирующих массу тела. В чем основа успеха? Ожирение и метаболизм. 2014;11(4):3-11. https://doi.org/10.14341/omet201443-11

For citation:


Babenko A.Yu., Neymark A.E., Anisimova K.A., Grineva Elena Nikolaevna E.N. Effects of bariatric surgery on the level of hormones that regulate body weight. What is the basis of success? Obesity and metabolism. 2014;11(4):3-11. (In Russ.) https://doi.org/10.14341/omet201443-11

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