Remission of nephrogenic diabetes insipidus (arginine vasopressin resistance): description of a rare clinical case
https://doi.org/10.14341/omet13007
Abstract
Nephrogenic diabetes insipidus is a heterogeneous disease in the etiopathogenesis of which are involved acquired and congenital factors. In this case, the kidneys do not respond to vasopressin and continue to produce large concentrated volumes of urine. Distinctive features in the pathology of central genesis are the fact of trauma, brain tumor with involvement of pituitary gland, response to intranasal vasopressin in the form of decreased diuresis.
For diagnosis it is important to perform a series of differential diagnostic tests.
In this article we present a unique clinical case of a patient with a long-term course of diabetes insipidus with the development a spectrum of comorbid conditions, metabolic disorders, required kidney transplantation.
About the Authors
R. M. Guseinova
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Raisat M. Guseinova - MD.
11 Dm. Ulyanova street, 117036 Moscow
Scopus Author ID: 58077013800; Researcher ID: HDO-1221-2022
Competing Interests:
Работа выполнена в соавторстве с заведующей редакцией журнала «Ожирение и метаболизм» Дзерановой Л.К. и членом редакционной коллегии журнала «Ожирение и метаболизм» Пигаровой Е.А.
E. A. Pigarova
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Ekaterina A. Pigarova - MD, PhD.
Moscow
Scopus Author ID: 55655098500; Researcher ID: T-9424-2018
Competing Interests:
Работа выполнена в соавторстве с заведующей редакцией журнала «Ожирение и метаболизм» Дзерановой Л.К. и членом редакционной коллегии журнала «Ожирение и метаболизм» Пигаровой Е.А.
L. K. Dzeranova
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Larisa K. Dzeranova - MD, PhD.
Moscow
Competing Interests:
Работа выполнена в соавторстве с заведующей редакцией журнала «Ожирение и метаболизм» Дзерановой Л.К. и членом редакционной коллегии журнала «Ожирение и метаболизм» Пигаровой Е.А.
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Supplementary files
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1. Figure 1. Mechanism of urine concentration by vasopressin in the collecting duct. | |
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| Type | Исследовательские инструменты | |
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For citations:
Guseinova R.M., Pigarova E.A., Dzeranova L.K. Remission of nephrogenic diabetes insipidus (arginine vasopressin resistance): description of a rare clinical case. Obesity and metabolism. 2024;21(1):92-98. (In Russ.) https://doi.org/10.14341/omet13007
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