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Drugs for the treatment of central diabetes insipidus: historical background and modern opportunities

https://doi.org/10.14341/omet2017117-23

Abstract

Central diabetes insipidus is a severe disease with disturbance of arginine vasopressin secretion, which leads to excretion of large amounts of hypotonic urine. The polyuria-polydipsia syndrome is essential as a clinical presentation and high impact condition. Desmopressin, a synthetic analog of arginine vasopressin, is used to compensate a water-electrolyte balance is available in forms of tablets and intranasal spray. Free drug choice is obligated for proper treatment.

About the Authors

Dar'ya S. Mikhaylova

Endocrinology Research Centre


Russian Federation

postgraduate student


Competing Interests:

конфликт интересов отсутствует



Ekaterina A. Pigarova

Endocrinology Research Centre


Russian Federation

PhD


Competing Interests:

конфликт интересов отсутствует



Larisa K. Dzeranova

Endocrinology Research Centre


Russian Federation

ScD


Competing Interests:

конфликт интересов отсутствует



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Mikhaylova D.S., Pigarova E.A., Dzeranova L.K. Drugs for the treatment of central diabetes insipidus: historical background and modern opportunities. Obesity and metabolism. 2017;14(1):17-23. (In Russ.) https://doi.org/10.14341/omet2017117-23

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