Non-classical effects of vitamin D
https://doi.org/10.14341/omet2018112-18
Abstract
Some studies support the involvement of vitamin D in modulating the inflammatory response and developing diabetes. Since the activation of inflammatory biomarkers, cytokines and pathways interferes with normal metabolism and disrupts proper insulin signaling and insulin resistance, it is hypothesized that vitamin D could influence lipid and glucose homeostasis by modulating inflammatory response and renin-angiotensin system. In this review discussed the mechanisms of the influence of vitamin D on metabolic disease.
About the Author
Lilit V. EgshatyanEndocrinology Research Centre; A.I. Evdokimov Moscow State University of Medicine and Dentistry
Russian Federation
PhD
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1. Fig. 1. Adapted by Leung et al. [37]. The influence of vitamin D on lipogenesis, the synthesis and accumulation of triglycerides and gluconeogenesis in the liver. | |
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2. Fig. 2. Adapted by Leung et al. [58]. The hyperglycemia-induced expression of PAC components can be prevented by calcitriol. | |
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Egshatyan L.V. Non-classical effects of vitamin D. Obesity and metabolism. 2018;15(1):12-18. (In Russ.) https://doi.org/10.14341/omet2018112-18
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