Metabolic disorders in adipocytokine imbalance and gestational complications
https://doi.org/10.14341/omet201719-16
Abstract
Adipose tissue as an endocrine organ synthesizes a large number of biologically active substances, adipocytokines, which have both local and systemic effects influencing the vascular wall, tissue sensitivity to insulin, glucose metabolism, and systemic inflammation. The data obtained from clinical and experimental studies demonstrate the close relationship between the imbalance of adipocytokines and pregnancy complications such as insulin resistance, gestational diabetes, and preeclampsia. In this connection, close attention of obstetrician-gynecologists and endocrinologists is focused on etiopathogenic aspects of the formation of gestational complications with metabolic disorders caused by an imbalance of adipocytokines with maternal obesity and to the search for markers of these disorders. The review presents the current literature data on adipose tissue hormones and their influence on the course of a gestational process.
About the Authors
Natalya B. ChabanovaTyumen State Medical University
Russian Federation
PhD, associate Professor at Obstetrics and gynecology department
Sergey I. Mataev
Мultiprofile medical center «Limfomed»
Russian Federation
ScD, Professor
Tatiana N. Vasilkova
Tyumen State Medical University
Russian Federation
ScD, Professor at Department of hospital therapy with course of Endocrinology and Phthisiology
Irina A. Troshina
Tyumen State Medical University
Russian Federation
ScD, Professor at Department of hospital therapy with course of Endocrinology and Phthisiology
Competing Interests:
д.м.н., профессор кафедры госпитальной терапии с курсом эндокринологии и фтизиатрии
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For citations:
Chabanova N.B., Mataev S.I., Vasilkova T.N., Troshina I.A. Metabolic disorders in adipocytokine imbalance and gestational complications. Obesity and metabolism. 2017;14(1):9-16. (In Russ.) https://doi.org/10.14341/omet201719-16

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