Сircadian rhythm and metabolic effects of melatonin
https://doi.org/10.14341/omet2015146-51
Abstract
Sleep is a highly important process, required for normal organ and system function. Researchers assume, that during sleep brain shifts to internal body signals. Therefore, any sleep disturbance will disrupt health. Industrial and post-industrial society links high stress level and sleep problems. Excess light stimulation in living space, including bedroom, disorganize circadian rhythm of melatonin. Besides regulation this hormone has antioxidant and adaptogen functions. From psychological standpoint the same high-stress social context depletes the adaptation resources. To normalize sleep function we can utilize both sleep hygiene measures and modern pharmacotherapy. There are melatonin-based drugs, which help to restore sleep-wake cycle, augment adaptive capability and in some cases empower the existing treatment for specific somatic maladies. From a clinical and chronobiological standpoint melatonin is useful in broad spectrum of disorders.
About the Author
Denis Igorevich Burchakov
Endocrinology Research Centre
Russian Federation
Somnology doctor
Russian Federation
Somnology doctor
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Review
For citations:
Burchakov D.I. Сircadian rhythm and metabolic effects of melatonin. Obesity and metabolism. 2015;12(1):46-51. (In Russ.) https://doi.org/10.14341/omet2015146-51
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