Effects of bariatric surgery on the level of hormones that regulate body weight. What is the basis of success?
https://doi.org/10.14341/omet201443-11
Abstract
The growth of obesity and type 2 diabetes incidence has made bariatric surgery a widespread method of treatment. The effectiveness of bariatric
operations in the treatment of obesity and related metabolic diseases is thoroughly highlighted in medical literature. However, the results
of surgery do not always correlate with type of operation. As before, the mechanisms have not been fully studied of how the bariatric surgery
influence on insulinresistance, entero-insulin axes, adipokines. Understanding such mechanisms will allow us to determine more precisely the
indications relating to surgical treatment, and enhance the effectiveness of surgery in specific patient. The review is focusing on the influence of
various types of bariatric surgery on the level of adipokines and incretines that participate in regulation of appetite and of fat and carbohydrate
metabolism. The article elaborates modern concepts related to the impact of bariatric operations on metabolic disorders in obesity.
About the Authors
Alina Yur'evna Babenko
Federal Almazov Medical Research Centre
Russian Federation
MD, PhD, associate professor
Russian Federation
MD, PhD, associate professor
Aleksandr Evgen'evich Neymark
Federal Almazov Medical Research Centre
Pavlov First Saint Petersburg State Medical University
Russian Federation
Ph.D, a leading researcher at Federal Almazov Medical Research CentreAssociate Professor at Faculty Surgery Department
Russian Federation
Ph.D, a leading researcher at Federal Almazov Medical Research CentreAssociate Professor at Faculty Surgery Department
Kristina Aleksandrovna Anisimova
Federal Almazov Medical Research Centre
Pavlov First Saint Petersburg State Medical University
Russian Federation
clinical residence
Russian Federation
clinical residence
Elena Nikolaevna Nikolaevna Grineva Elena Nikolaevna
Federal Almazov Medical Research Centre
Russian Federation
MD, Ph.D, Professor, director of the Institute of Endocrinology
Russian Federation
MD, Ph.D, Professor, director of the Institute of Endocrinology
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For citations:
Babenko A.Yu., Neymark A.E., Anisimova K.A., Grineva Elena Nikolaevna E.N. Effects of bariatric surgery on the level of hormones that regulate body weight. What is the basis of success? Obesity and metabolism. 2014;11(4):3-11. (In Russ.) https://doi.org/10.14341/omet201443-11
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