Methods for guantificative assessment of insulin resistance
https://doi.org/10.14341/2071-8713-5313
Abstract
The article delineates the definition of concept of insulin resistance as well as the factors that determine tissue insulin sensitivity; defines the conception of «insulin resistance syndrome» (metabolic syndrome), its criteria and diseases that it accompanies. It is pointed that the golden standard for quantitative assessment of insulin action is hyperinsulinemic euglycemic clamp. Different indexes for indirect measurement of insulin resistance and possibilities of use of mathematical models for this matter are discussed.
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