Metabolic abnormalities and behavioral peculiarities in patients with obesity: statics and dynamics on Orlistat therapy
https://doi.org/10.14341/2071-8713-5242
Abstract
Obesity causes variety of metabolic disorders, and decreases the quality of life. At the same time many people with BMI>30 kg/A possess different psychopathologic disturbances. The results of ourwork disclose high percentage of impaired carbohydrate metabolism, hyperlipidemia, and resistance to insulin in patients with obesity Besides, it was revealed that more than a half of the patients have symptoms of maladjustment, and decreased quality of life. Reduction of body w eight due to the treatment with Orlistat w as accompanied by improvement in parameters of carbohydrate and lipid metabolism and quality of life
References
1. Метаболический синдром: патогенез, клиника, диагностика, подходы к лечению С.А. Бутрова: Эндокринологический научный центр РАМН, Москва (РМЖ).
2. Bray G.A.; Bellanger T. Pennington Biomedical Research Center, Baton Rouge, L.A, USA. Epidemiology, trends, and morbidities of obesity and the metabolic syndrome. Endocrine. 2006; 29(1):109-17 (ISSN: 0969-711X).
3. Barrett-Connor E.L Obesity, atherosclerosis, and coronary artery disease // Ann. Intern. Med.-1985.-Vol. 103.-P. 1010-1019.
4. Basseches H.I., Karp S.A. Field dependence in young anorectic and obese women // Psychother Psychosom. 1984. - Vol. 41. - №1. - P. 33-37.
5. Carpenter K.M., Hasin D.S., Faith M.S., Allison K.S. Relationships between obesity and DSM-IV major depressive disorder, suicide ideation, and suicide attempts: results from a general population study. Am. J. Public. Health. 2000. Feb; 90(2):251 -7.
6. Chiadi U. Onyike, Rosa M. Crum, Hochang B. Lee, Constantine G. Lyketsos and William W. Eaton. (Third National Health and Nutrition Examination Survey, NHANES III). Onyike et al. Am. J. Epidemiol. 2003; 158: 1139-1147.
7. De Chouly, De Lenclave M.B., Florequin C, Bailly D. Obesity, alexithymia, psychopathology and binge eating: a comparative study of 40 obese patients and 32 controls // Encephale. 2001. - Vol. 27. - №4. - P. 343-350.
8. Erbersdobler H.F. Institut f ür Humanern ährung und Lebensmittelkunde, Düsternbrooker Weg 17, D-24105 Kiel. Epidemiology and management of obesity in Germany Int J Vitam Nutr Res. 2006; 76(4): 257-9 (ISSN: 0300-9831).
9. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) // JAMA. - 2001. - Vol. 285. - P. 2486-2497.
10. Helen A. Doll, Sophie E.K. Petersen and Sarah L. Stewart-Brown. Obesity and physical and emotional well-being: associations between body mass index, chronic illness, and the physical and mental components of the SF-36 questionnaire//Obesity Research 8:160-170 (2000).
11. Herman С.Р., Polivv J. External cues in the control of food intake in humans: the sensory-normative distinction // Physiol. Behav. 2008. - Vol. 94. - №5. - P. 722-728.
12. Hansson S.B., Ryden 0.0. Relationship between differentiation and integration of self and nonself: an investigation in terms of modes of perceptual adaptation // Percept. Mot. Skills. 1987. - Vol. 64. - №2. - P. 523-538.
13. Higgs S. Cognitive influences on food intake: the effects of manipulating memory for recent eating // Physiol. Behav. 2008. - Vol. 94. - №5. - P. 734-749.
14. John B. Dixon, MBBS, FRACGP; Maureen E.Dixon, BSc; Paul E. О ' Brien, MD, FRACS. Depression in Association With Severe Obesity//Arch. Intern. Med.-2003; 163:2058-2065.
15. Martin Donohoe, MD, FACP. Weighty Matters: Public Health Aspects of the Obesity Epidemic. Part I. Causes and Health and Economic Consequences of Obesity. Posted 12/12/2007.
16. Meyers A.W., Stunkard A.J., Coll M. Food accessibility and food choice. A test of Schachter's externality hypothesis//Arch Gen Psychiatry. 1980. - Vol. 37. -№10.-P. 1133-1135.
17. Mann G.V. The influence of obesity on health // N. Engl. J. Med. - 1974. - Vol. 291.-P. 178-185,226-232.
18. Ryden A, Sullivan M., Torgerson J.S., Karlsson J., Lindroos A.-K. andTaft С Severe obesity and personality: a comparative controlled study of personality traits. International Journal of Obesity (2003) 27,1534-1540. doi:10.1038/sj.ijo.0802460.
19. Rand C.S., Stunkard A.J. Obesity and psychoanalysis: treatment and four-year follow-up//Am J. Psychiatry 1983.-Vol. 140. - P. 1140-1144.
20. Stunkard A.J., Faith M.S., Allison K.S. Depression and obesity. Biol Psychiatry. 2003; 54(3):330-7.
21. Urdapilleta I., Mirabel-Sarron C., Meunier J.M., Richard J.F. Study of the categorization process among patients with eating disorders: a new cognitive approach to psychopathology//Encephale. 2005. -Vol. 31(1 Pt. 1). -P. 82-91.
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, , , Metabolic abnormalities and behavioral peculiarities in patients with obesity: statics and dynamics on Orlistat therapy. Obesity and metabolism. 2009;6(3):27-38. (In Russ.) https://doi.org/10.14341/2071-8713-5242
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