Dynamics of adipose tissue changes measured by MRI in obese patients during Reduxin treatment
https://doi.org/10.14341/2071-8713-5128
Abstract
Objective. To study the influence of the drug Reduxine in obese patients on the distribution of adipose tissue measured by MRI. Methods. In an open, prospective, non-randomized study duration of 20 weeks included 31 obese patients aged 20 to 65 years. During the study, the anthropometric parameters and the dynamics of the area of adipose tissue by means of MR imaging. Results. Weight loss in patients averaged 9.0 kg. Clinically significant weight loss reached 23 people (79%). Median reduction in waist circumference was 10 cm. Dynamic assessment of adipose tissue by MRI was performed in 17 patients. Reduxine treatment induced statistically significant decrease of both visceral and subcutaneous fat. Conclusions. According to the results of MRI, the reduction in waist circumference in patients receiving Reduxine occurred by reducing the number of both subcutaneous and visceral fat in the abdominal area.
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, , Dynamics of adipose tissue changes measured by MRI in obese patients during Reduxin treatment. Obesity and metabolism. 2012;9(4):39-43. (In Russ.) https://doi.org/10.14341/2071-8713-5128
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