Prospects for the use of polyphenols in patients with bronchial asthma and obesity
https://doi.org/10.14341/omet13092
Abstract
Asthma and obesity are diseases characterized by variability in the course and possible complications, the frequency of which is steadily increasing from year to year. The correlation between obesity and asthma is still an acute problem of the health care system. Representing very common diseases, they aggravate each other’s course and significantly worsen the quality of life. Polyphenols are a promising option to solve the existing problem. These low molecular weight compounds are biologically active substances capable of influencing on many metabolic processes in the body. This review demonstrates the multiple properties of these unique micronutrients, including antioxidant, anti-carcinogenic, anti-inflammatory, metabolic, neuroprotective and many others. The integration of polyphenols into the daily diet can contribute to strengthening public health, reducing the frequency and progression of socially significant diseases, and using these compounds in diseases such as asthma and obesity, according to numerous modern studies, it is possible to achieve a significant therapeutic effect at all. The purpose of this literature review is to trace the correlation between the effect of using polyphenols and changes in the course of the disease and quality of life in patients with asthma on the background of obesity, based on facts from advanced sources.
About the Authors
V. A. Beloglazov
Order of the Red Banner of Labor S.I. Georgievsky Medical Institute V.I. Vernadsky Crimean Federal University
Russian Federation
Competing Interests:
Russian Federation
Vladimir A. Beloglazov, MD, PhD, Professor, Department of Internal Medicine №2
5/7 Lenin Boulevard street, 295051 Simferopol
Competing Interests:
None
I. A. Yatskov
Order of the Red Banner of Labor S. I. Georgievsky Medical Institute V. I. Vernadsky Crimean Federal University
Russian Federation
Competing Interests:
Russian Federation
Igor A. Yatskov, PhD, Department of Internal Medicine №2
5/7 Lenin Boulevard street, 295051 Simferopol
Competing Interests:
None
A. A. Moik
Order of the Red Banner of Labor S. I. Georgievsky Medical Institute V. I. Vernadsky Crimean Federal University
Russian Federation
Competing Interests:
Russian Federation
Anastasia A. Moik, Department of Internal Medicine №2
5/7 Lenin Boulevard street, 295051 Simferopol
Competing Interests:
None
Andrey Vladimirovich Moik
Order of the Red Banner of Labor S. I. Georgievsky Medical Institute V. I. Vernadsky Crimean Federal University
Russian Federation
Competing Interests:
Russian Federation
Andrey V. Moik, Department of Internal Medicine №2
5/7 Lenin Boulevard street, 295051 Simferopol
Competing Interests:
None
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Supplementary files
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1. Figure 1. The complex influence of the inflammatory, metabolic and mechanical pathways contributes to the progression of asthma in obese patients. | |
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2. Figure 2. The effect on the transmission of mTOR signals using dietary polyphenols in the prevention of obesity. | |
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Beloglazov V.A., Yatskov I.A., Moik A.A., Moik A.V. Prospects for the use of polyphenols in patients with bronchial asthma and obesity. Obesity and metabolism. 2024;21(4):357-364. (In Russ.) https://doi.org/10.14341/omet13092
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