Preview

Obesity and metabolism

Advanced search

Efficacy of interventions for prevention and correction of overweight and obesity in children 7–8 years old: a meta-analysis

https://doi.org/10.14341/omet12120

Abstract

The rapid increase in overweight and obesity in children is a global public health problem. Interventions to reduce the prevalence of obesity before puberty are considered to be the most effective, but the results of trials are not consistent enough. We performed a meta-analysis of the efficacy of interventions to prevent or correct overweight and obesity in pre-pubertal children. Thirty-one Cochrane systematic reviews were analyzed, the results of 10 RCTs and two prospective comparative studies were extracted. All trials had an moderate or high risk of bias. According to the results of meta-analyzes, the prevention of overweight and obesity through recommendations of lifestyle modification is effective, the difference in a BMI decrease is -0.19, 95% CI [-0.35; -0.03], compared with the absence of intervention, in children 7–8 years old if applied within 2–4 years, but not within one year or less. The effect of non-drug interventions in children with overweight or obesity was not revealed.

About the Authors

Vlada K. Fediaeva
The Center for Healthcare Quality Assessment and Control; Scientific and research financial institute
Russian Federation


Elena A. Bogova
Endocrinology Research Centre
Russian Federation

MD, PhD



Valentina A. Peterkova
Endocrinology Research centre
Russian Federation

MD, PhD, professor, academician of RAS



Olga Yu. Rebrova
Endocrinology Research Centre; The Russian National Research Medical University named after N.I. Pirogov
Russian Federation

MD, PhD



References

1. Abarca-Gómez L, Abdeen ZA, Hamid ZA, et al. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults. Lancet. 2017;390(10113):2627-2642. DOI:10.1016/s0140-6736(17)32129-3

2. World Health Organization Europe. The challenge of obesity in the WHO European Region. Fact Sheet EURO/13/05. Copenhagen, Bucharest, 2005 September 12.

3. Дедов И.И., Мельниченко Г.А., Бутрова С.А., и др. Ожирение у подростков в России // Ожирение и метаболизм. — 2006. — Т. 3. — №4. — C. 30-34. [Dedov II, Mel’nichenko GA, Butrova SA, et al. Ozhirenie u podrostkov v Rossii. Obesity and metabolism. 2006;3(4):30-34. (In Russ.)] DOI:10.14341/2071-8713-5141

4. Тутельян В.А., Батурин А.К., Конь И.Я., и др. Распространенность ожирения и избыточной массы тела среди детского населения РФ: мультицентровое исследование // Педиатрия. Журнал им. Г.Н. Сперанского. — 2014. — Т. 93. — №5. — С. 28-31. [Tutel’yan VA, Baturin AK, Kon’ IY, et al. Rasprostranennost’ ozhireniya i izbytochnoy massy tela sredi detskogo naseleniya RF: mul’titsentrovoe issledovanie. Pediatriia. 2014;93(5):28-31. (In Russ.)]

5. Ахмедова Р.М., Софронова Л.В., Трефилов Р.Н. Распространенность и гендерные особенности ожирения у подростков Перми // Вопросы современной педиатрии. — 2014. — Т. 13. — №5. — С. 37-41. [Ahmedova RM, Sofronova LV, Trefilov RN. Prevalence and gender characteristics of obesity in adolescents in the city of Perm. Current pediatrics. 2014;13(5):37-41. (In Russ.)] DOI:10.15690/vsp.v13i5.1148

6. Соболева Н.П., Руднев С.Г., Николаев Д.В., и др. Биоимпедансный скрининг населения России в центрах здоровья: распространенность избыточной массы тела и ожирения // РМЖ. — 2014. — Т. 20. — №4. — С. 4-13. [Soboleva NP, Rudnev SG, Nikolayev DV, et al. The bio-impedance screening of population in health centers: prevalence of surplus body mass and obesity. RMZh. 2014;20(4):4-13. (In Russ.)]

7. Павловская Е.В. Коморбидная патология при ожирении у детей: клинико-метаболическая характеристика, оценка эффективности диетотерапии: Дис. … д-ра мед. наук. — М.; 2020. [Pavlovskaya EV. Komorbidnaya patologiya pri ozhirenii u detey: kliniko-metabolicheskaya kharakteristika, otsenka effektivnosti dietoterapii. [dissertation] Moscow; 2020. (In Russ.)]

8. MacLean PS, Higgins JA, Giles ED, et al. The role for adipose tissue in weight regain after weight loss. Obes Rev. 2015;16 Suppl 1:45-54. DOI:10.1111/obr.12255

9. Стародубова А.В. Факторы риска, особенности формирования и течения сердечно-сосудистых заболеваний у женщин с ожирением разных возрастных групп и возможности их коррекции: Дис. … д-ра мед. наук. — М.; 2015. [Starodubova AV. Faktory riska, osobennosti formirovaniya i techeniya serdechno-sosudistykh zabolevaniy u zhenshchin s ozhireniem raznykh vozrastnykh grupp i vozmozhnosti ikh korrektsii. [dissertation] Moscow; 2015. (In Russ.)]

10. Камалова А.А. Современные подходы к профилактике ожирения у детей // Российский вестник перинатологии и педиатрии. — 2016. — Т. 61. — №6. — С. 43-48. [Kamalova AA. Current approaches to preventing childhood obesity. Rossiiskii vestnik perinatologii i pediatrii. 2016;61(6):43-48. (In Russ.)] DOI:10.21508/1027-4065-2016-61-6-43-48

11. Weihrauch-Bluher S, Schwarz P, Klusmann JH. Childhood obesity: increased risk for cardiometabolic disease and cancer in adulthood. Metabolism. 2019;92:147-152. DOI:10.1016/j.metabol.2018.12.001

12. Kim J, Must A, Fitzmaurice GM, et al. Incidence and remission rates of overweight among children aged 5 to 13 years in a district-wide school surveillance system. Am J Public Health. 2005;95(9):1588-1594. DOI:10.2105/AJPH.2004.054015

13. Waters E, de Silva-Sanigorski A, Hall BJ, et al. Interventions for preventing obesity in children. Cochrane Database Syst Rev. 2011(12):CD001871. DOI:10.1002/14651858.CD001871.pub3

14. Mead E, Brown T, Rees K, et al. Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years. Cochrane Database Syst Rev. 2017;6:CD012651. DOI:10.1002/14651858.CD012651

15. Martin A, Booth JN, Laird Y, et al. Physical activity, diet and other behavioural interventions for improving cognition and school achievement in children and adolescents with obesity or overweight. Cochrane Database Syst Rev. 2018;3:CD009728. DOI:10.1002/14651858.CD009728.pub4

16. Brown T, Moore TH, Hooper L, et al. Interventions for preventing obesity in children. Cochrane Database Syst Rev. 2019;7:CD001871. DOI:10.1002/14651858.CD001871.pub4

17. Baranowski T, Baranowski JC, Cullen KW, et al. The fun, food, and fitness project (FFFP): the Baylor GEMS pilot study. Ethn Dis. 2003;13(1 Suppl 1):S30-39.

18. Caballero B, Clay T, Davis SM, et al. Pathways: a school-based, randomized controlled trial for the prevention of obesity in American Indian schoolchildren. Am J Clin Nutr. 2003;78(5):1030-1038. DOI:10.1093/ajcn/78.5.1030

19. Donnelly JE, Greene JL, Gibson CA, et al. Physical Activity Across the Curriculum (PAAC): a randomized controlled trial to promote physical activity and diminish overweight and obesity in elementary school children. Prev Med. 2009;49(4):336-341. DOI:10.1016/j.ypmed.2009.07.022

20. James J, Thomas P, Cavan D, Kerr D. Preventing childhood obesity by reducing consumption of carbonated drinks: cluster randomised controlled trial. BMJ. 2004;328(7450):1237. DOI:10.1136/bmj.38077.458438.EE

21. Marcus C, Nyberg G, Nordenfelt A, et al. A 4-year, cluster-randomized, controlled childhood obesity prevention study: STOPP. Int J Obes (Lond). 2009;33(4):408-417. DOI:10.1038/ijo.2009.38

22. Paineau DL, Beaufils F, Boulier A, et al. Family dietary coaching to improve nutritional intakes and body weight control: a randomized controlled trial. Arch Pediatr Adolesc Med. 2008;162(1):34-43. DOI:10.1001/archpediatrics.2007.2

23. Sanigorski AM, Bell AC, Kremer PJ, et al. Reducing unhealthy weight gain in children through community capacity-building: results of a quasi-experimental intervention program, Be Active Eat Well. Int J Obes (Lond). 2008;32(7):1060-1067. DOI:10.1038/ijo.2008.79

24. Taylor RW, McAuley KA, Barbezat W, et al. Two-year follow-up of an obesity prevention initiative in children: the APPLE project. Am J Clin Nutr. 2008;88(5):1371-1377. DOI:10.3945/ajcn.2007.25749

25. Kalavainen MP, Korppi MO, Nuutinen OM. Clinical efficacy of group-based treatment for childhood obesity compared with routinely given individual counseling. Int J Obes (Lond). 2007;31(10):1500-1508. DOI:10.1038/sj.ijo.0803628

26. Johnston CA, Moreno JP, El-Mubasher A, et al. Impact of a school-based pediatric obesity prevention program facilitated by health professionals. J Sch Health. 2013;83(3):171-181. DOI:10.1111/josh.12013

27. Brandstetter S, Klenk J, Berg S, et al. Overweight prevention implemented by primary school teachers: a randomised controlled trial. Obes Facts. 2012;5(1):1-11. DOI:10.1159/000336255

28. Magnusson KT, Hrafnkelsson H, Sigurgeirsson I, et al. Limited effects of a 2-year school-based physical activity intervention on body composition and cardiorespiratory fitness in 7-year-old children. Health Educ Res. 2012;27(3):484-494. DOI:10.1093/her/cys049

29. Реброва О.Ю., Федяева В.К., Хачатрян Г.Р. Адаптация и валидизация вопросника для оценки риска систематических ошибок в рандомизированных контролируемых испытаниях // Медицинские технологии. Оценка и выбор. — 2015. — Т. 19. — №1. — C. 9-17. [Rebrova OY, Fedyaeva VK, Khachatryan GR. Adaptation and Validation of the Cochrane Questionnarie to Assess Risks of Bias in Randomized Controlled Trials. Medical technologies. 2015;19(1):9-17. (In Russ.)]

30. Training.cochrane.org [Internet]. Julian PT Higgins, Jelena Savović, Matthew J Page, et al. Chapter 8: Assessing risk of bias in a randomized trial [cited 2020 Aug 10]. Available from: https://training.cochrane.org/handbook/current/chapter-08.

31. Витебская А.В., Писарева Е.А., Попович А.В. Образ жизни детей и подростков с ожирением. Результаты анкетирования пациентов и их родителей // Ожирение и метаболизм. — 2016. — Т. 13. — №2. — С. 33-40. [Vitebskaya AV, Pisareva EA, Popovich AV. Lifestyle in children and adolescents with obesity: results of the survey of patients and their parents. Obesity and metabolism. 2015;13(2):33-40. (In Russ.)] DOI:10.14341/omet2016233-40

32. McGovern L, Johnson JN, Paulo R, et al. Treatment of Pediatric Obesity: A Systematic Review and Meta-Analysis of Randomized Trials. J Clin Endocrinol Metab. 2008;93(12):4600-4605. DOI:10.1210/jc.2006-2409

33. Ануфриева Е.В. Основные закономерности формирования, прогнозирования здоровья детей школьного возраста и совершенствование системы медицинского обеспечения в образовательных организациях: Дис. … д-ра мед. наук. – Екатеринбург; ٢٠١٩. [Anufrieva EV. Osnovnye zakonomernosti formirovaniya, prognozirovaniya zdorov’ya detey shkol’nogo vozrasta i sovershenstvovanie sistemy meditsinskogo obespecheniya v obrazovatel’nykh organizatsiyakh. [dissertation] Ekaterinburg; 2019. (In Russ.)]

34. Liu Z, Xu HM, Wen LM, et al. A systematic review and meta-analysis of the overall effects of school-based obesity prevention interventions and effect differences by intervention components. Int J Behav Nutr Phys Act. 2019;16(1):95. DOI:10.1186/s12966-019-0848-8


Supplementary files

1. Figure 1. Flowchart for selecting systematic reviews (SRs) for further consideration.
Subject
Type Other
View (189KB)    
Indexing metadata ▾
2. Table 2. Risks of systematic bias by domain * [13-16] and the resulting risk **
Subject
Type Other
View (94KB)    
Indexing metadata ▾
3. Figure 2. Meta-analysis of changes in body mass index with the use of preventive interventions lasting up to 1 year. A - funnel-shaped plot for assessing publication bias; B - meta-analysis itself.
Subject
Type Other
View (276KB)    
Indexing metadata ▾
4. Figure 3. Meta-analysis of changes in body mass index with the use of preventive interventions lasting 2–4 years. A - funnel-shaped plot for assessing publication bias; B - meta-analysis itself.
Subject
Type Other
View (327KB)    
Indexing metadata ▾
5. Figure 4. Meta-analysis of changes in body mass index in the period of 0.5–2 years, therapeutic interventions. A - funnel-shaped plot for assessing publication bias; B - meta-analysis itself.
Subject
Type Other
View (254KB)    
Indexing metadata ▾

Review

For citations:


Fediaeva V.K., Bogova E.A., Peterkova V.A., Rebrova O.Yu. Efficacy of interventions for prevention and correction of overweight and obesity in children 7–8 years old: a meta-analysis. Obesity and metabolism. 2020;17(2):115-124. (In Russ.) https://doi.org/10.14341/omet12120

Views: 2092


ISSN 2071-8713 (Print)
ISSN 2306-5524 (Online)