Metabolic changes in patients with familial pituitary adenomas associated with mutations in the AIP gene
Tatiana S. Tarasova,
Ekaterina A. Pigarova,
Larisa K. Dzeranova,
Anatoly N. Tiulpakov, 
Ivan I. Dedov
Ivan I. Dedov https://doi.org/10.14341/omet2017148-51
Abstract
Currently, many AIP mutations responsible for the development of pituitary adenomas have been described. Penetence of pituitary adenomas in AIP-positive FIPA families is incomplete and varies widely. Data on the characteristics of metabolic changes in patients with familial pituitary adenomas associated with mutations in the AIP gene continues to be inadequate. Evaluation of the results of molecular genetic studies, as well as a thorough analysis of metabolic changes in these clinical cases, will help to develop and improve diagnostic and treatment algorithms, identify patient groups that require special attention of endocrinologists, timely screening, aggressive treatment, and careful dynamic observation.
About the Authors
Tatiana S. TarasovaEndocrinology Research Centre
Russian Federation
Postgraduate student
Competing Interests:
Конфликт интересов отсутствует
Ekaterina A. Pigarova
Endocrinology Research Centre
Russian Federation
PhD
Competing Interests:
Конфликт интересов отсутствует
Larisa K. Dzeranova
Endocrinology Research Centre
Russian Federation
ScD
Competing Interests:
Конфликт интересов отсутствует
Anatoly N. Tiulpakov
Endocrinology Research Centre
Russian Federation
ScD
Competing Interests:
Конфликт интересов отсутствует
Ivan I. Dedov
Endocrinology Research Centre
Russian Federation
ScD, prof., Vice-president of Russian Academy of Sciences
Competing Interests:
Конфликт интересов отсутствует
References
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For citations:
Tarasova T.S., Pigarova E.A., Dzeranova L.K., Tiulpakov A.N., Dedov I.I. Metabolic changes in patients with familial pituitary adenomas associated with mutations in the AIP gene. Obesity and metabolism. 2017;14(1):48-51. (In Russ.) https://doi.org/10.14341/omet2017148-51
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