Use of bariatric surgery in patients with type 2 diabetes: help to the practitioner
https://doi.org/10.14341/omet2016150-56
Abstract
The use of bariatric surgery in patients with obesity and type 2 diabetes mellitus (T2DM) has its own features. In this lecture we discuss indications and contraindications for bariatric surgery, including specific, e.g. presence of type 2 diabetes. Various types of bariatric surgery and the mechanisms of their effects on glucose and lipid metabolism. We show the results of the restrictive and bypass bariatric surgery in patients with obesity and type 2 diabetes, we present requirements for bariatric surgery and parameters of assessment of its effectiveness, including remission of type 2 diabetes after bariatric surgery. The reasons postsurgical hypoglycemia, as well as predictors of effectiveness of bariatric surgery for the metabolic control in patients with obesity and type 2 diabetes.
About the Authors
Ekaterina V. Ershova
Endocrinology Research Centre
Russian Federation
researcher at the the Therapy Department with a group of obesity
Russian Federation
researcher at the the Therapy Department with a group of obesity
Ekaterina A. Troshina
Endocrinology Research Centre
Russian Federation
MD, Ph.D. Professor, Head of the Therapy Department with a group of obesity
Russian Federation
MD, Ph.D. Professor, Head of the Therapy Department with a group of obesity
References
1. Дедов И.И., Яшков Ю.И., Ершова Е.В. Инкретины и их влияние на течение сахарного диабета 2 типа у пациентов с морбидным ожирением после бариатрических операций // Ожирение и метаболизм. – 2012. – Т. 9. – №2 – C. 3-10. [Dedov II, Yashkov YI, Ershova EV. Incretins and their influence on the course of type 2 diabetes in patients with morbid obesity after bariatric oper. Obesity and metabolism. 2012;9(2):3-10. (In Russ.)] doi:10.14341/omet201223-10
2. Ершова Е.В., Яшков Ю.И. Состояние углеводного и липидного обмена у пациентов с ожирением и сахарным диабетом 2 типа после билиопанкреатического шунтирования // Ожирение и метаболизм. – 2013. – Т. 10. – №3 – C. 28-36. [Ershova EV, Yashkov YI. Status of carbohydrate and lipid metabolism in obese patients with type 2 diabetes mellitus after biliopancreatic diversion surgery. Obesity and metabolism. 2013;10(3):28-36. (In Russ.)] doi: 10.14341/2071-8713-3862
3. Бондаренко И.З., Бутрова С.А., Гончаров Н.П., и др. Лечение морбидного ожирения у взрослых // Ожирение и метаболизм. – 2011. – Т. 8. – №3 – C. 75-83.. Ожирение и метаболизм. 2011; 3: 75-83. [Bondarenko IZ, Butrova SA, Goncharov NP, et al. Lechenie morbidnogo ozhireniya u vzroslykhNatsional'nye klinicheskie rekomendatsii. Obesity and metabolism. 2011;8(3):75-83. (In Russ.)] doi: 10.14341/2071-8713-4844
4. Яшков Ю.И., Ершова Е.В. «Метаболическая» хирургия // Ожирение и метаболизм. – 2011. – Т. 8. – №3 – C. 13-17. [ Yashkov YI, Ershova EV. «Metabolicheskaya» khirurgiya. Obesity and metabolism. 2011;8(3):13-17. (In Russ.)] doi: 10.14341/2071-8713-4831
5. Яшков Ю.И., Никольский А.В., Бекузаров Д.К., и др. Cемилетний опыт применения операции билиопанкреатического отведения в модификации Hess-Marceau в лечении морбидного ожирения и сахарного диабета 2 типа // Ожирение и метаболизм. – 2012. – Т. 9. – №2 – C. 43-48. [Yashkov YI, Nikol'skiy AV, Bekuzarov DK, et al. A 7-year experience with the surgery of biliopancreatic diversion in the modification of Hess-Marceau for the treatment of morbid obesity and type 2 diabetes. Obesity and metabolism. 2012;9(2):43-48. (In Russ.)] doi:10.14341/omet2012243-48
6. Standards of Medical Care in Diabetes--2014. Diabetes Care. 2013;37(Supplement_1):S14-S80. doi:10.2337/dc14-S014
7. Buchwald H, Estok R, Fahrbach K, Banel D, Jensen MD, Pories WJ, et al. Weight and Type 2 Diabetes after Bariatric Surgery: Systematic Review and Meta-analysis. The American Journal of Medicine. 2009;122(3):248-56.e5. doi:10.1016/j.amjmed.2008.09.041
8. Buchwald H., Varco R. Metabolic Surgery. New York: Grune& Stratton; 1978:chap 11.
9. Buse JB, Caprio S, Cefalu WT, et al.How Do We Define Cure of Diabetes? Diabetes Care. 2009;32(11):2133-5. doi:10.2337/dc09-9036
10. Drucker DJ. The role of gut hormones in glucose homeostasis. Journal of Clinical Investigation. 2007;117(1):24-32. doi:10.1172/jci30076
11. Flancbaum L. Mechanisms of Weight Loss After Surgery for Clinically Severe Obesity. Obesity Surgery. 1999;9(6):516-23. doi:10.1381/096089299765552585
12. Heber D, Greenway FL, Kaplan LM, et al. Endocrine and Nutritional Management of the Post-Bariatric Surgery Patient: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism. 2010;95(11):4823-43. doi:10.1210/jc.2009-2128
13. Holst J, Vilsboll T, Deacon C. The incretin system and its role in type 2 diabetes mellitus. Molecular and Cellular Endocrinology. 2009;297(1-2):127-36. doi:10.1016/j.mce.2008.08.012
14. IDF taskforce on the epidemiology and prevention, 2011.
15. Fried M, Yumuk V, Oppert J, et al. I Interdisciplinary European guidelines on metabolic and bariatric surgery. Obesity surgery. 2014;24(1):42-55.
16. Mason EE. The Mechanisms of Surgical Treatment of Type 2 Diabetes. Obesity Surgery. 2005;15(4):459-61. doi:10.1381/0960892053723330
17. Nauck MA. Unraveling the Science of Incretin Biology. The American Journal of Medicine. 2009;122(6):S3-S10. doi:10.1016/j.amjmed.2009.03.012
18. Patti ME, Goldfine AB. Hypoglycaemia following gastric bypass surgery — diabetes remission in the extreme? Diabetologia. 2010;53(11):2276-9. doi:10.1007/s00125-010-1884-8
19. Pories WJ, Dohm GL. Full and durable remission of type 2 diabetes? Through surgery? Surgery for Obesity and Related Diseases. 2009;5(2):285-8. doi:10.1016/j.soard.2008.12.006
20. Rabiee A, Magruder JT, Salas-Carrillo R, et al.Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass: Unraveling the Role of Gut Hormonal and Pancreatic Endocrine Dysfunction. Journal of Surgical Research. 2011;167(2):199-205. doi:10.1016/j.jss.2010.09.047
21. Rubino F, Gagner M. Potential of Surgery for Curing Type 2 Diabetes Mellitus. Annals of Surgery. 2002;236(5):554-9. doi:10.1097/00000658-200211000-00003
22. Rubino F, Kaplan LM, Schauer PR, Cummings DE. The Diabetes Surgery Summit Consensus Conference. Annals of Surgery. 2010;251(3):399-405. doi:10.1097/SLA.0b013e3181be34e7
Review
For citations:
Ershova E.V., Troshina E.A. Use of bariatric surgery in patients with type 2 diabetes: help to the practitioner. Obesity and metabolism. 2016;13(1):50-56. (In Russ.) https://doi.org/10.14341/omet2016150-56
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