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A rare case of a combination of metabolic and genetic changes in one patient (multiple endocrine neoplasia type 1 syndrome and Williams syndrome)

https://doi.org/10.14341/omet13195

Abstract

Asthma and obesity are diseases characterized by variability in the course and possible complications, the frequency of which is steadily increasing from year to year. The correlation between obesity and asthma is still an acute problem of the health care system. Representing very common diseases, they aggravate each other’s course and significantly worsen the quality of life. Polyphenols are a promising option to solve the existing problem. These low molecular weight compounds are biologically active substances capable of influencing on many metabolic processes in the body. This review demonstrates the multiple properties of these unique micronutrients, including antioxidant, anti-carcinogenic, anti-inflammatory, metabolic, neuroprotective and many others. The integration of polyphenols into the daily diet can contribute to strengthening public health, reducing the frequency and progression of socially significant diseases, and using these compounds in diseases such as asthma and obesity, according to numerous modern studies, it is possible to achieve a significant therapeutic effect at all. The purpose of this literature review is to trace the correlation between the effect of using polyphenols and changes in the course of the disease and quality of life in patients with asthma on the background of obesity, based on facts from advanced sources

About the Authors

E. E. Filkina
Endocrinology Research Centre
Russian Federation

Ekaterina E. Filkina

11 Dm. Ulyanova street, 117292 Moscow


Competing Interests:

None



E. G. Przhiyalkovskaya
Endocrinology Research Centre
Russian Federation

Elena G. Przhiyalkovskaya, MD, PhD

11 Dm. Ulyanova street, 117292 Moscow


Competing Interests:

None



A. A. Lazareva
Endocrinology Research Centre
Russian Federation

Anna A. Lazareva, MD

11 Dm. Ulyanova street, 117292 Moscow


Competing Interests:

None



M. Yu. Yukina
Endocrinology Research Centre
Russian Federation

Marina Yu. Yukina, MD, PhD

11 Dm. Ulyanova street, 117292 Moscow

Researcher ID: P-5181-2015

 

Scopus Author ID: 57109367700


Competing Interests:

None



References

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Supplementary files

1. Figure 1. Patient E. Typical changes in appearance in Williams syndrome.
Subject
Type Исследовательские инструменты
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For citations:


Filkina E.E., Przhiyalkovskaya E.G., Lazareva A.A., Yukina M.Yu. A rare case of a combination of metabolic and genetic changes in one patient (multiple endocrine neoplasia type 1 syndrome and Williams syndrome). Obesity and metabolism. 2024;21(4):425-430. (In Russ.) https://doi.org/10.14341/omet13195

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ISSN 2071-8713 (Print)
ISSN 2306-5524 (Online)