Advantages of physical activity of varying intensity for patients with type 1 diabetes and its influence on glucose metabolism

T. Yu. Demidova; V. V. Titova

doi:10.14341/omet12394

Advantages of physical activity of varying intensity for patients with type 1 diabetes and its influence on glucose metabolism

T. Yu. Demidova, V. V. Titova

https://doi.org/10.14341/omet12394

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Abstract

Patients with type 1 diabetes mellitus (T1DM) have many benefits from regular exercise, including improved quality of life, lower blood pressure, improved lipid profile, increased insulin sensitivity, decreased insulin dose requirements, improved endothelial function, and reduced risk of micro- and macrovascular complications, as well as overall mortality. Despite these benefits, T1DM patients often do not get enough physical activity (PA) and are less physically active than their non-diabetic peers. The main reason for the low PA in patients with T1DM is the difficulty of glycemic management and the fear of developing hypoglycemia during exercise. Different types of training, such as moderate to high intensity exercise, high intensity interval training, have different effects on glycemic activity during exercise, which can be used to prevent the development of hypoglycemic reactions during and after exercise, along with carbohydrate intake and insulin dose adjustment. Higher-intensity exercise, as well as greater frequency and duration, are associated with a greater reduction in the risk of overall and cardiovascular mortality. Regular physical activity has a positive effect on reducing the risk of micro- and macrovascular complications, general and cardiovascular mortality in patients with type 1 diabetes, regardless of the quality of glycemic control, which can be used for prevention of T1DM complications.

Keywords

type 1 diabetes mellitus, exercise, insulin therapy, aerobic exercise, anaerobic exercise, interval exercise, hypoglycemia

About the Authors

T. Yu. Demidova

Pirogov Russian National Research Medical University (RNRMU)
Russian Federation

Tatyana Yu. Demidova, MD, PhD, Professor

Moscow

eLibrary SPIN: 9600-9796

Competing Interests:

Демидова Т.Ю. — лектор, участник экспертных советов, клинических исследований компаний Astra Zeneca, Novo Nordisk, Sanofi, Novartis, Boehringer Ingelheim, Takeda, Berlin Chemi.

V. V. Titova

Pirogov Russian National Research Medical University (RNRMU)
Russian Federation

Victoria V. Titova, MD

1 Ostrovitynova street, 117997 Moscow

eLibrary SPIN: 7864-2910

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Supplementary files

	1. Figure 1. Data from flash monitoring of the glycemia of patient D. with type 1 diabetes mellitus against the background of aerobic physical load (running of moderate intensity (70% HRmax)), while taking 15 g of carbohydrates before exercise without changing doses of insulin. Immediately after the start of the exercise, the glycemic level significantly decreased from 6.6 mmol/L to 3.9 mmol/L and continued to decrease after the end of the exercise. Hypoglycemia during and after exercise was stopped by taking 30 g (in total) of easily digestible carbohydrates.
	Subject
	Type	Исследовательские инструменты
	View (163KB)	Indexing metadata ▾

	2. Figure 2. Data from flash monitoring of the glycemia of patient D. with type 1 diabetes mellitus against the background of high-intensity interval training (10 × 30 s sprint (~ 90% HRmax), during the break, low-intensity jogging (50% HRmax) 2 min). The insulin dose did not change before exercise, and carbohydrates were not consumed. The glycemic level after the start of the exercise decreased from 7.3 mmol/L to 4.3 mmol/L. At the end of the workout, the patient took 12 g of carbohydrates.
	Subject
	Type	Исследовательские инструменты
	View (178KB)	Indexing metadata ▾

Review

For citations:

Demidova T.Yu., Titova V.V. Advantages of physical activity of varying intensity for patients with type 1 diabetes and its influence on glucose metabolism. Obesity and metabolism. 2020;17(4):385-392. (In Russ.) https://doi.org/10.14341/omet12394

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).

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	Title	Figure 1. Data from flash monitoring of the glycemia of patient D. with type 1 diabetes mellitus against the background of aerobic physical load (running of moderate intensity (70% HRmax)), while taking 15 g of carbohydrates before exercise without changing doses of insulin. Immediately after the start of the exercise, the glycemic level significantly decreased from 6.6 mmol/L to 3.9 mmol/L and continued to decrease after the end of the exercise. Hypoglycemia during and after exercise was stopped by taking 30 g (in total) of easily digestible carbohydrates.
	Type	Исследовательские инструменты
	Date	2021-03-09
Digital Object Identifier	https://doi.org/10.14341/omet12394-5876

	Title	Figure 2. Data from flash monitoring of the glycemia of patient D. with type 1 diabetes mellitus against the background of high-intensity interval training (10 × 30 s sprint (~ 90% HRmax), during the break, low-intensity jogging (50% HRmax) 2 min). The insulin dose did not change before exercise, and carbohydrates were not consumed. The glycemic level after the start of the exercise decreased from 7.3 mmol/L to 4.3 mmol/L. At the end of the workout, the patient took 12 g of carbohydrates.
	Type	Исследовательские инструменты
	Date	2021-03-09
Digital Object Identifier	https://doi.org/10.14341/omet12394-5878

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Obesity and metabolism

Advantages of physical activity of varying intensity for patients with type 1 diabetes and its influence on glucose metabolism

Full Text:

Abstract

Keywords

About the Authors

References

Supplementary files

Review

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