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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet9729</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-9729</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original paper</subject></subj-group></article-categories><title-group><article-title>Сравнение точности оценки основного обмена в покое у детей с простым ожирением при использовании расчетных формул и метода непрямой респираторной калориметрий</article-title><trans-title-group xml:lang="en"><trans-title>Comparison of the accuracy of resting metabolic rate in children with simple obesity using calculation formulas and indirect respiratory calorimetry</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9834-727X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Окороков</surname><given-names>Павел Леонидович</given-names></name><name name-style="western" xml:lang="en"><surname>Okorokov</surname><given-names>Pavel L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">pokorokov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9299-1053</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васюкова</surname><given-names>Ольга Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Vasyukova</surname><given-names>Olga V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">o.vasyukova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2604-1703</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ширяева</surname><given-names>Татьяна Юрьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Shiryaeva</surname><given-names>Tatiana Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н, доцент</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">tasha-home@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ФГБУ &amp;laquo;Национальный медицинский исследовательский центр эндокринологии&amp;raquo; Минздрава России&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinology Research Center&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>16</day><month>09</month><year>2019</year></pub-date><volume>16</volume><issue>2</issue><fpage>54</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Окороков П.Л., Васюкова О.В., Ширяева Т.Ю., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Окороков П.Л., Васюкова О.В., Ширяева Т.Ю.</copyright-holder><copyright-holder xml:lang="en">Okorokov P.L., Vasyukova O.V., Shiryaeva T.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/9729">https://www.omet-endojournals.ru/jour/article/view/9729</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Обязательным условием при планировании рациона питания с целью снижения веса у детей с ожирением является определение уровня основного обмена в покое (RMR – от англ. resting metabolic rate). Золотым стандартом оценки суточных энергозатрат покоя является непрямая респираторная калориметрия, однако, учитывая ее высокую стоимость и трудоемкость, в клинической практике широко используются различные расчетные формулы.</p><p>Цель исследования – определение точности оценки основного обмена в покое с помощью расчетных формул у детей с простым ожирением по сравнению с эталонным методом – непрямой респираторной калориметрией.</p></sec><sec><title>Методы</title><p>Методы. В исследование включены 100 детей в возрасте от 9 до 18 лет, с «простым» конституционально-экзогенным ожирением, которым была проведена оценка основного обмена в покое с помощью расчетных формул и непрямой респираторной калориметрии.</p></sec><sec><title>Результаты</title><p>Результаты. Формула Molnar наиболее точно оценивает уровень основного обмена в покое, сопоставимый с результатами непрямой респираторной калориметрии в 64% случаев. Формулы Harris–Benedict и IOM позволяют получить точный результат в 53 и 51% случаев соответственно. Наименее точный результат демонстрирует формула, предложенная ВОЗ (22%). Минимальная средняя разность между расчетным и фактическим значением основного обмена в покое у мальчиков с ожирением для формулы Molnar: 18 ккал (ДИ -53– 90; 95% LOA -490–527), у девочек: -0,7 ккал (ДИ -65–63; 95% LOA -435–434). Обращают на себя внимание большая средняя разница и широкий разброс границ согласия исследуемых показателей у детей с ожирением.</p><p>При оценке в зависимости от степени ожирения показано, что наибольшей точностью обладает формула Molnar, однако у детей с морбидным ожирением аккуратность оценки значительно снижается.</p></sec><sec><title>Заключение</title><p>Заключение. Непрямая респираторная калориметрия является предпочтительным методом оценки основного обмена в покое у детей с простым ожирением.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>BACKGROUND</title><p>BACKGROUND: A prerequisite for planning a diet for weight loss in obese children is to determine the level of resting metabolic rate (RMR). The gold standard for estimating the daily energy consumption of rest is indirect respiratory calorimetry. However, given its high cost and labor intensity, various calculation formulas are widely used in clinical practice.</p></sec><sec><title>AIMS</title><p>AIMS: to determine the accuracy of resting metabolic rate estimated by calculation formulas and indirect respiratory calorimetry in children with simple obesity.</p></sec><sec><title>MATERIALS AND METHODS</title><p>MATERIALS AND METHODS: The study included 100 children aged 9 to 18 years, with a «simple» constitutional-exogenous obesity, which assessed the resting metabolic rate estimated by calculation formulas and indirect respiratory calorimetry.</p></sec><sec><title>RESULTS</title><p>RESULTS: The Molnar formula most accurately estimates resting metabolic rate, comparable to the results of indirect respiratory calorimetry in 64% of cases. The Harris-Benedict and IOM formulas yield an accurate result in 53 and 51% of the cases, respectively. The least accurate result is shown by WHO formula (22%). The minimum mean difference between the calculated and actual basal metabolic rate in obese boys for the Molnar formula is 18 kcal (CI: -53 to 90, 95% LOA from -490 to 527), in girls: -0.7 kcal (CI) : -65 - 63, 95% LOA from -435 to 434). Attention is drawn to the large mean difference and wide spread of the boundaries of the agreement of the studied indicators in obese children. In the evaluation, depending on the degree of obesity, it is shown that the formula Molnar has the highest accuracy, however, in children with morbid obesity, the accuracy of the evaluation is significantly reduced.</p></sec><sec><title>CONCLUSIONS</title><p>CONCLUSIONS: Indirect respiratory calorimetry is the preferred method of assessing resting metabolic rate in children with simple obesity.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>детское ожирение</kwd><kwd>основной обмен в покое</kwd><kwd>непрямая респираторная калориметрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pediatric obesity</kwd><kwd>basal metabolism</kwd><kwd>calorimetry</kwd><kwd>indirect</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Российская ассоциация эндокринологов, Российское общество по профилактике неинфекционных болезней, Ассоциация детских кардиологов России. 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