ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/omet2018143-49ometendo-9435Research ArticleСлучай из практикиCase ReportОжирение и кахексия в качестве первых проявлений папиллярной краниофарингиомыObesity and cahexia as the first manifestations of craniopharingiomahttps://orcid.org/0000-0003-4480-1902АстафьеваЛюдмила ИгоревнаAstafievaLiudmila I.

д.м.н.

Sc.D.

last@nsi.ruhttps://orcid.org/0000-0002-7440-4687КлочковаИрина СергеевнаKlochkovaIrina S.

врач

IKlochkova@nsi.ruhttps://orcid.org/0000-0001-9333-9473КалининПавел ЛьвовичKalininPavel L.

д.м.н., заведущий 8 отделением

Sc.D.

pkalinin@nsi.ruhttps://orcid.org/0000-0001-8344-3381КадашевБорис АлександровичKadashevBoris A.

д.м.н., профессор, главный научный сотрудник

Sc.D., Professor

Kadashev@nsi.ruКоноваловАлександр НиколаевичKonovalovAleksandr N.

д.м.н., профессор, академик РАН, научный руководитель ФГАУ НМИЦН РФ

Sc.D., prof., academician of RAS

AKonovalov@nsi.ruhttps://orcid.org/0000-0002-5323-1000ФомичевДмитрий ВладиславовичFomichevDmitrii V.

к.м.н., старший научный сотрудник

PhD

dfomichev@nsi.ruhttps://orcid.org/0000-0002-6520-4296КутинМаксим АлександровичKutinMaksim A.

к.м.н., старший научный сотрудник 

PhD

kutin@nsi.ruhttps://orcid.org/0000-0003-3777-5662ШариповОлег ИльдаровичSharipovOleg I.

к.м.н.

PhD

osharipov@nsi.ruhttps://orcid.org/0000-0003-2733-5874СидневаЮлия ГеннадьевнаSidnevaYlia G.

к.м.н.

PhD

ysidneva@nsi.ruhttps://orcid.org/0000-0001-7726-2242ЯценкоДина АлександровнаYatsenkoDina A.

врач

MD

dinochka-d@mail.ruhttps://orcid.org/0000-0002-0327-4619ДзерановаЛариса КонстантиновнаDzeranovaLarisa K.

д.м.н, главный научный сотрудник

Sc.D

dzeranovalk@yandex.ru<p>ФГАУ &laquo;Нaциональный медицинский исследовательский центр нейрохирургии имени академика Н.Н. Бурденко&raquo; Минздрава РФ</p>Россия<p>N.N. Burdenko National Medical Research Center of Neurosurgery</p>Russian Federation<p>ФГБОУ ДПОРМАНПО Минздрава РФ</p>Россия<p>FGBU RMANPO</p>Russian Federation<p>ФГБУ &laquo;Нaциональный медицинский исследовательский центр эндокринологии&raquo; Минздрава России</p>Россия<p>Endocrinology Research Centre</p>Russian Federation2018250420181514349Copyright &#x00A9; Астафьева Л.И., Клочкова И.С., Калинин П.Л., Кадашев Б.А., Коновалов А.Н., Фомичев Д.В., Кутин М.А., Шарипов О.И., Сиднева Ю.Г., Яценко Д.А., Дзеранова Л.К., 20182018Астафьева Л.И., Клочкова И.С., Калинин П.Л., Кадашев Б.А., Коновалов А.Н., Фомичев Д.В., Кутин М.А., Шарипов О.И., Сиднева Ю.Г., Яценко Д.А., Дзеранова Л.К.Astafieva L.I., Klochkova I.S., Kalinin P.L., Kadashev B.A., Konovalov A.N., Fomichev D.V., Kutin M.A., Sharipov O.I., Sidneva Y.G., Yatsenko D.A., Dzeranova L.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/9435

Ключевой структурой в регуляции энергетического гомеостаза является гипоталамус. Поражение гипоталамической области может приводить к дисбалансу энергообмена с развитием ожирения или кахексии. Наиболее часто обменные нарушения встречаются при краниофарингиомах. В статье представлены два клинических наблюдения папиллярной краниофарингиомы (КФ) у молодых женщин. Оба случая сопровождались нарушением энергетического баланса, в одном – с развитием ожирения, в другом – кахексии.

The key structure in the regulation of energy homeostasis is the hypothalamus. The damage of the hypothalamic region can lead to imbalance of energy exchange with the development of obesity or cachexia. The most common metabolic disorders occur in case of craniopharyngiomas. The article presents two clinical observations of papillary craniopharyngioma in young women. Cases were accompanied by different disturbances of the energy balance, in one - with the development of obesity, in the other - cachexia.

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The authors declare that there are no conflicts of interest present.