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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet2018119-24</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-8808</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Научные исследования</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original studies</subject></subj-group></article-categories><title-group><article-title>Конъюгированная линолевая кислота и её влияние на увеличение скорости снижения веса и улучшение антропометрических показателей у молодых мужчин с избыточной массой тела на протяжении комплексной программы по снижению веса</article-title><trans-title-group xml:lang="en"><trans-title>Conjugated linoleic acid accelerates weight loss and improves anthropometric measures in overweight young adult males during weight loss program</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0407-0685</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аккила</surname><given-names>Самех Самеер</given-names></name><name name-style="western" xml:lang="en"><surname>Akkila</surname><given-names>Sameh S.</given-names></name></name-alternatives><bio xml:lang="en"><p>Lecturer, Department of Anatomy, Histology &amp; Embryology University of Mustansiriyah, Faculty of Medicine</p></bio><email xlink:type="simple">samakkila@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;Университет Мустанcири&lt;/p&gt;</institution><country>Ирак</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Al-Mustansiriya University&lt;/p&gt;</institution><country>Iraq</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>25</day><month>04</month><year>2018</year></pub-date><volume>15</volume><issue>1</issue><fpage>19</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аккила С.С., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Аккила С.С.</copyright-holder><copyright-holder xml:lang="en">Akkila S.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/8808">https://www.omet-endojournals.ru/jour/article/view/8808</self-uri><abstract><sec><title>Исходная информация</title><p>Исходная информация: С увеличением распространенности ожирения в Ираке возрастает приверженность к физической активности среди молодых людей. В то же время увеличение количества предлагаемых пищевых добавок способствует улучшению физической формы и позволяет избавиться от лишнего веса. Конъюгированная линолевая кислота (СLA – сonjugated linoleic acid) часто используется для такой цели.</p></sec><sec><title>Цель</title><p>Цель: Текущее исследование было предназначено в целях апробирования действия конъюгированной линолевой кислоты и ее способности действительно ускорять снижение веса в сочетании с диетой и умеренными физическими упражнениями, а также исследование их сочетанного эффекта в отношении атропометрических показателей при ожирении.</p></sec><sec><title>Объекты и методы</title><p>Объекты и методы: 60 молодых мужчин добровольцев были включены в исследование, которое предполагало использование диеты с пониженным содержанием углеводов и жиров, а также комплекс высокоинтенсивных умеренных физических упражнений с временным интервалом (HIIT – high intensity interval exercise). 40 из них получали конъюгированную линолевую кислоту (1000 мг/день) в течение 8 недель, в то время как оставшиеся 20 участников составили контрольную группу. Индекс массы тела (body mass index – BMI), отношение окружности талии к окружности бедер (waist/hip ratio – WHR), сагиттальный абдоминальный диаметр (sagittal abdominal diameter – SAD), процент содержания жира в организме (body adiposity index – BAI) были зарегистрированы в начале, после 4 и 8 недель исследования.</p></sec><sec><title>Результаты</title><p>Результаты: Группа участников, которая употребляла конъюгированную линолевую кислоту, показала существенно большее снижение всех показателей в конце исследования. В контрольной группе снижение показателей было значительным, но такие показатели как BMI и SAD оказались менее сниженными, чем в основной группе, однако WHR и BAI оставались аналогичными. Процент изменений отличался между 1-ой и 2-ой частями исследования, также показаны статистические различия между двумя группами и для различных показателей. Наиболее важным явилось то, что SAD снизился значительно быстрее за время первых 4-х недель исследования, указывая на преимущественное уменьшение висцерального жира. Напротив, WHR снизился за время 2-ой половины изучения, больше за счет снижения абдоминального жирового депо.</p></sec><sec><title>Обсуждение</title><p>Обсуждение: Независимо от механизма действиям СLA, ускорение действия в снижении веса происходит только в комбинации с диетой и физической активностью. Это также соответствует преимущественно естественному снижению более метаболически активного висцерального жира до перехода к снижению подкожного жира. Является ли данная пищевая добавка эффективной или нет, требует дальнейшего изучения.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background: With the increasing prevalence of obesity in Iraq, an increasing trend towards better physical fitness has emerged among young adults. At the same time, an increasing number of dietary supplements is offered to improve fitness and shed the extra weight. Conjugated linoleic acid (CLA) is commonly used for such purpose.</p></sec><sec><title>Aim</title><p>Aim: The current study was designed to test if CLA can actually accelerate weight loss when combined with dieting and moderate exercise and to examine its effect on anthropometric measures of obesity.</p></sec><sec><title>Subjects &amp; methods</title><p>Subjects &amp; methods: Sixty young males enrolled willingly in the study and were put on a low-carbohydrate low-fat diet and moderate high intensity interval exercise (HIIT) program. Forty of them were given CLA (1000 mg/day) for 8 weeks while the remaining twenty served as control group. Body mass index (BMI), waist/hip ratio (WHR), sagittal abdominal diameter (SAD) and body adiposity index (BAI) were recorded as baseline and again after 4 and 8 weeks.</p></sec><sec><title>Results</title><p>Results: The CLA-treated group showed significantly greater reduction in all four measures by the end of the study. The control group had significant but less decrease in BMI &amp; SAD but not in WHR or BAI. The percent change difference between the first and second four weeks of the study also showed statistical difference among the two groups and for different measures. The most significant finding was that SAD dropped more rapidly during the first 4 weeks of the study indicating a preferential loss of visceral fat. Oppositely, WHR dropped during the second half of the study indicating loss of more abdominal fat stores.</p></sec><sec><title>Discussion</title><p>Discussion: Regardless of the mode of action of CLA, its accelerative effect in weight loss is augmented by the combination with dieting and physical activity. It also corresponds to the natural body preference to losing the more metabolically active visceral fat prior to switching to the loss of subcutaneous fat. Whether or not this effect is sustainable requires further study.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>избыточная масса тела</kwd><kwd>ожирение</kwd><kwd>конъюгированная линолевая кислота</kwd><kwd>индекс массы тела</kwd><kwd>соотношение окружности талии к окружности бедер</kwd><kwd>сагиттальный абдоминальный диаметр</kwd><kwd>процент содержания жира в организме</kwd><kwd>висцеральный жир</kwd><kwd>подкожный жир</kwd></kwd-group><kwd-group xml:lang="en"><kwd>overweight</kwd><kwd>obesity</kwd><kwd>conjugated linoleic acid</kwd><kwd>body mass index</kwd><kwd>waist/hip ratio</kwd><kwd>sagittal abdominal diameter</kwd><kwd>body adiposity index</kwd><kwd>visceral fat</kwd><kwd>subcutaneous fat</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">The World Fact Book. [Internet] CIA. Central Intelligence Agency. [22 June 2014. Retrieved: 1 June 2017]. 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