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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet2016332-36</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-8206</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзор литературы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Лечение сахарного диабета 2 типа: устойчивость сахароснижающего действия препаратов</article-title><trans-title-group xml:lang="en"><trans-title>Treatment of type 2 diabetes: the stability of the effectiveness of hypoglycemic medications</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Моргунова</surname><given-names>Татьяна Борисовна</given-names></name><name name-style="western" xml:lang="en"><surname>Morgunova</surname><given-names>Tat'yana</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">tanmorgun@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фадеев</surname><given-names>Валентин Викторович</given-names></name><name name-style="western" xml:lang="en"><surname>Fadeev</surname><given-names>Valentin</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">tanmorgun@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБOУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov’s First Moscow State Medical University, Moscow, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>09</day><month>11</month><year>2016</year></pub-date><volume>13</volume><issue>3</issue><fpage>32</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Моргунова Т.Б., Фадеев В.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Моргунова Т.Б., Фадеев В.В.</copyright-holder><copyright-holder xml:lang="en">Morgunova T., Fadeev V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/8206">https://www.omet-endojournals.ru/jour/article/view/8206</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>лечение</kwd><kwd>ингибиторы дипептидилпептидазы-4</kwd><kwd>устойчивость сахароснижающего действия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>treatment</kwd><kwd>DPP-4 inhibitors</kwd><kwd>glycemic durability</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Godinho R, Mega C, Teixeira-de-Lemos E, et al. 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