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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet2015447-51</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-7839</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Лекция</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Lecture</subject></subj-group></article-categories><title-group><article-title>Патогенетические основы развития сердечно-сосудистых заболеваний при ожирении. Трудности диагностики и лечения</article-title><trans-title-group xml:lang="en"><trans-title>The pathogenic basis for the development of cardiovascular disease in obesity: difficulties of diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бондаренко</surname><given-names>Ирина Зиятовна</given-names></name><name name-style="western" xml:lang="en"><surname>Bondarenko</surname><given-names>Irina Ziatovna</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., главный научный сотрудник отделения интервенционной кардиологии</p></bio><bio xml:lang="en"><p>MD PhD, Chief Researcher at Interventional Cardiology Department</p></bio><email xlink:type="simple">iz_bondarenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шпагина</surname><given-names>Ольга Викторовна</given-names></name><name name-style="western" xml:lang="en"><surname>Shpagina</surname><given-names>Ol'ga Viktorovna</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант</p></bio><bio xml:lang="en"><p>postgraduate student</p></bio><email xlink:type="simple">shpagina_olga@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Эндокринологический научный центр Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>16</day><month>03</month><year>2016</year></pub-date><volume>12</volume><issue>4</issue><fpage>47</fpage><lpage>51</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бондаренко И.З., Шпагина О.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Бондаренко И.З., Шпагина О.В.</copyright-holder><copyright-holder xml:lang="en">Bondarenko I.Z., Shpagina O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/7839">https://www.omet-endojournals.ru/jour/article/view/7839</self-uri><abstract><p>Сердечно-сосудистые нарушения, связанные с морбидным ожирением, включают гипертрофию миокарда, расширение полостей сердечной мышцы, снижение насосной функции сердца. В целом ожирение предрасполагает к многочисленным сердечно-сосудистым осложнениям, таким как ишемическая болезнь сердца, сердечная недостаточность и внезапная сердечная смерть. Клиническая оценка сердечно-сосудистой системы пациентов с морбидным ожирением ограничена морфологическими и структурными изменениями, специфическими для большой жировой массы тела. Внезапная или необъяснимаясмерть у пациентов с морбидным ожирением часто является манифестацией скрытых сердечно-сосудистых заболеваний.</p></abstract><trans-abstract xml:lang="en"><p>Cardiovascular abnormalities associated with morbid obesity include cardiac hypertrophy, cardiac dilatation, diastolic dysfunction. Also obesity predispose to numerous cardiac complications such as coronary heart disease, heart failure, and sudden death. The cardiovascular clinical evaluation of obese patients may be limited by morphological changes, which are specific for increased amount of body fat mass. The incidence of sudden and unexplained death in morbid obesity may be a manifestation of occult cardiovascular disease in this population.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>сердечно-сосудистые заболевания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>cardiovascular diseases.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dagenais GR et al. (2005) Prognostic impact of body weight and abdominal obesity in women and men with cardiovascular disease. Am Heart J 149: 54–60;</mixed-citation><mixed-citation xml:lang="en">Dagenais GR et al. (2005) Prognostic impact of body weight and abdominal obesity in women and men with cardiovascular disease. Am Heart J 149: 54–60;</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Wong CY et al. 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