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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet2015418-22</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-7831</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзор литературы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Применение Ксеникала в клинической практике</article-title><trans-title-group xml:lang="en"><trans-title>Xenical in clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ершова</surname><given-names>Екатерина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Ershova</surname><given-names>Ekaterina Vladimirovna</given-names></name></name-alternatives><bio xml:lang="ru"><p>научный сотрудник отделения терапии с группой ожирения</p></bio><bio xml:lang="en"/><email xlink:type="simple">yu99pol06@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Екатерина Анатольевна</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>Ekaterina Anatol'evna</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующая отделением терапии с группой ожирения</p></bio><bio xml:lang="en"/><email xlink:type="simple">troshina@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комшилова</surname><given-names>Ксения Андреевна</given-names></name><name name-style="western" xml:lang="en"><surname>Komshilova</surname><given-names>Kseniya Andreevna</given-names></name></name-alternatives><bio xml:lang="ru"><p>научный сотрудник отделения терапии с группой ожирения</p></bio><bio xml:lang="en"/><email xlink:type="simple">kom-ksusha@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Эндокринологический научный центр Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>09</day><month>03</month><year>2016</year></pub-date><volume>12</volume><issue>4</issue><fpage>18</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ершова Е.В., Трошина Е.А., Комшилова К.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Ершова Е.В., Трошина Е.А., Комшилова К.А.</copyright-holder><copyright-holder xml:lang="en">Ershova E.V., Troshina E.A., Komshilova K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/7831">https://www.omet-endojournals.ru/jour/article/view/7831</self-uri><abstract/><trans-abstract xml:lang="en"><p>The basis of the treatment of obesity is changing eating pattern, combined with increased physical activity. However, not all patients can change their eating habits and lifestyle. This dictates a necessity to include pharmacotherapy in complex treatment of obesity. Currently, the drug of choice for the treatment of patients with complicated obesity is orlistat – peripheral drug, which exert its therapeutic effect within the gastrointestinal tract and has no systemic actions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>лечение</kwd><kwd>питание</kwd><kwd>физическая активность</kwd><kwd>орлистат.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>treatment</kwd><kwd>nutrition</kwd><kwd>physical activity</kwd><kwd>orlistat</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бутрова С. А. Метаболический синдром: патогенез, клиника, диагностика, подходы к лечению //Русский медицинский журнал. – 2001. – Т. 9. – №. 2. – С. 56-60. 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