<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet2016371-75</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-7735</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Случай из практики</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Клинический случай прогрессирования хронической болезни почек у пациента с первичным гиперпаратиреозом с последующей трансплантацией почки</article-title><trans-title-group xml:lang="en"><trans-title>Chronic kidney disease progression in a patient with primary hyperparathyroidism</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирная</surname><given-names>Cветлана Сергеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Mirnaya</surname><given-names>Svetlana Sergeevna</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант</p></bio><bio xml:lang="en"/><email xlink:type="simple">littlegoo@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мокрышева</surname><given-names>Наталья Георгиевна</given-names></name><name name-style="western" xml:lang="en"><surname>Mokrysheva</surname><given-names>Natalia Georgievna</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заместитель директора Центра</p><p>д.м.н.</p></bio><bio xml:lang="en"/><email xlink:type="simple">nm70@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ "Эндокринологический научный центр" Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>05</day><month>02</month><year>2016</year></pub-date><volume>13</volume><issue>3</issue><fpage>71</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мирная C.С., Мокрышева Н.Г., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Мирная C.С., Мокрышева Н.Г.</copyright-holder><copyright-holder xml:lang="en">Mirnaya S.S., Mokrysheva N.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/7735">https://www.omet-endojournals.ru/jour/article/view/7735</self-uri><abstract><p>В последнее время эндокринологи все реже встречаются со случаями тяжелого течения первичного гиперпаратиреоза (ПГПТ). ПГПТ в большинстве случаев выявляется на более ранней стадии, что связано с улучшением информированности врачей разных специальностей об этом заболевании.</p><p>Представлен клинический случай крайне тяжелого поражения почек у пациента с мочекаменной болезнью с ПГПТ с исходом в терминальную стадию хронической болезни почек (ХБП), при котором прогрессирование ХБП продолжилось и после проведения хирургического лечения и привело к необходимости проведения заместительной почечной терапии и последующей трансплантации почки.</p></abstract><trans-abstract xml:lang="en"><p>Nowadays cases of severe primary hyperparathyroidism (PHPT) are rare. Doctors of different specialties are informed better about PHPT “masks” and overall PHPT is diagnosed much earlier. We present a case report of a patient with nephrolithiasis and primary hyperparathyroidism with both bone and visceral complications, who showed deterioration of renal function up to chronic kidney disease stage 5 and was referred to renal transplantation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>первичный гиперпаратиреоз</kwd><kwd>паратиреоидный гормон</kwd><kwd>ПТГ</kwd><kwd>хроническая болезнь почек</kwd><kwd>трансплантация почки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>primary hyperparathyroidism</kwd><kwd>parathyroid hormone</kwd><kwd>PTH</kwd><kwd>chronic kidney disease</kwd><kwd>renal transplantation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mihai R, Wass JAH, Sadler GP. Asymptomatic hyperparathyroidism ? need for multicentre studies. Clin Endocrinol (Oxf). 2007;0(0):070725144954001-??? doi: 10.1111/j.1365-2265.2007.02970.x.</mixed-citation><mixed-citation xml:lang="en">Mihai R, Wass JAH, Sadler GP. Asymptomatic hyperparathyroidism ? need for multicentre studies. Clin Endocrinol (Oxf). 2007;0(0):070725144954001-??? doi: 10.1111/j.1365-2265.2007.02970.x.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">МокрышеваН.Г., РожинскаяЛ.Я., ПеретокинаЕ.В., и др Анализ основных эпидемиологических характеристик первичного гиперпаратиреоза в России (по данным регистра) // Проблемы Эндокринологии. – 2012. – Т. 58. – №5 – C. 16-20. [Mokrysheva NG, Rozhinskaia LI, Peretokina EV, Rostomian LG, Mirnaia SS, Pronin VS, et al. The results of analysis of the major epidemiological characteristics of primary hyperparathyroidism in Russia based on the registry data. Problems of Endocrinology. 2012;58(5):16-20. (In Russ.)] doi:10.14341/probl201258516-20</mixed-citation><mixed-citation xml:lang="en">МокрышеваН.Г., РожинскаяЛ.Я., ПеретокинаЕ.В., и др Анализ основных эпидемиологических характеристик первичного гиперпаратиреоза в России (по данным регистра) // Проблемы Эндокринологии. – 2012. – Т. 58. – №5 – C. 16-20. [Mokrysheva NG, Rozhinskaia LI, Peretokina EV, Rostomian LG, Mirnaia SS, Pronin VS, et al. The results of analysis of the major epidemiological characteristics of primary hyperparathyroidism in Russia based on the registry data. Problems of Endocrinology. 2012;58(5):16-20. (In Russ.)] doi:10.14341/probl201258516-20</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Patel CN, Salahudeen HM, Lansdown M, Scarsbrook AF. Clinical utility of ultrasound and 99mTc sestamibi SPECT/CT for preoperative localization of parathyroid adenoma in patients with primary hyperparathyroidism. Clin Radiol. 2010;65(4):278-287. doi: 10.1016/j.crad.2009.12.005.</mixed-citation><mixed-citation xml:lang="en">Patel CN, Salahudeen HM, Lansdown M, Scarsbrook AF. Clinical utility of ultrasound and 99mTc sestamibi SPECT/CT for preoperative localization of parathyroid adenoma in patients with primary hyperparathyroidism. Clin Radiol. 2010;65(4):278-287. doi: 10.1016/j.crad.2009.12.005.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Scillitani A, Guarnieri V, Battista C, et al. Primary Hyperparathyroidism and the Presence of Kidney Stones Are Associated with Different Haplotypes of the Calcium-Sensing Receptor. J Clin Endocrinol Metab. 2007;92(1):277-283. doi: 10.1210/jc.2006-0857.</mixed-citation><mixed-citation xml:lang="en">Scillitani A, Guarnieri V, Battista C, et al. Primary Hyperparathyroidism and the Presence of Kidney Stones Are Associated with Different Haplotypes of the Calcium-Sensing Receptor. J Clin Endocrinol Metab. 2007;92(1):277-283. doi: 10.1210/jc.2006-0857.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fraser WD. Hyperparathyroidism. The Lancet. 2009;374(9684):145-158. doi: 10.1016/s0140-6736(09)60507-9.</mixed-citation><mixed-citation xml:lang="en">Fraser WD. Hyperparathyroidism. The Lancet. 2009;374(9684):145-158. doi: 10.1016/s0140-6736(09)60507-9.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Мокрышева Н.Г. Первичный гиперпаратиреоз (эпидемиология, клиника, современные принципы диагностики и лечения): Дис. … док. мед. наук. –Москва; 2011. [Mokrysheva NG.Pervichnyi giperparatireoz (epidemiologiya, klinika, sovremennyeprintsipydiagnostikiilecheniya) [dissertation] Moscow; 2011. (In Russ).]</mixed-citation><mixed-citation xml:lang="en">Мокрышева Н.Г. Первичный гиперпаратиреоз (эпидемиология, клиника, современные принципы диагностики и лечения): Дис. … док. мед. наук. –Москва; 2011. [Mokrysheva NG.Pervichnyi giperparatireoz (epidemiologiya, klinika, sovremennyeprintsipydiagnostikiilecheniya) [dissertation] Moscow; 2011. (In Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Khan AA, Bilezikian JP, Potts JT. The Diagnosis and Management of Asymptomatic Primary Hyperparathyroidism Revisited. J Clin Endocrinol Metab. 2009;94(2):333-334. doi: 10.1210/jc.2008-1757.</mixed-citation><mixed-citation xml:lang="en">Khan AA, Bilezikian JP, Potts JT. The Diagnosis and Management of Asymptomatic Primary Hyperparathyroidism Revisited. J Clin Endocrinol Metab. 2009;94(2):333-334. doi: 10.1210/jc.2008-1757.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Khosla S, Melton LJ, Wermers RA, et al. Primary Hyperparathyroidism and the Risk of Fracture: A Population-Based Study. J Bone Miner Res. 1999;14(10):1700-1707. doi: 10.1359/jbmr.1999.14.10.1700.</mixed-citation><mixed-citation xml:lang="en">Khosla S, Melton LJ, Wermers RA, et al. Primary Hyperparathyroidism and the Risk of Fracture: A Population-Based Study. J Bone Miner Res. 1999;14(10):1700-1707. doi: 10.1359/jbmr.1999.14.10.1700.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Borretta G, Gianotti L, Baffoni C, et al. Renal Function in Primary Hyperparathyroidism. 2010:P2-241-P242-241. doi: 10.1210/endo-meetings.2010.PART2.P5.P2-241.</mixed-citation><mixed-citation xml:lang="en">Borretta G, Gianotti L, Baffoni C, et al. Renal Function in Primary Hyperparathyroidism. 2010:P2-241-P242-241. doi: 10.1210/endo-meetings.2010.PART2.P5.P2-241.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Mollerup CL. Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled retrospective follow up study. BMJ. 2002;325(7368):807-807. doi: 10.1136/bmj.325.7368.807.</mixed-citation><mixed-citation xml:lang="en">Mollerup CL. Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled retrospective follow up study. BMJ. 2002;325(7368):807-807. doi: 10.1136/bmj.325.7368.807.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Tassone F, Gianotti L, Baffoni C, et al. Kdigo Categories of Glomerular Filtration Rate and Parathyroid Hormone Secretion in Primary Hyperparathyroidism. Endocr Pract. 2015;21(6):629-633. doi: 10.4158/ep14537.or.</mixed-citation><mixed-citation xml:lang="en">Tassone F, Gianotti L, Baffoni C, et al. Kdigo Categories of Glomerular Filtration Rate and Parathyroid Hormone Secretion in Primary Hyperparathyroidism. Endocr Pract. 2015;21(6):629-633. doi: 10.4158/ep14537.or.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Bilezikian JP, Brandi ML, Eastell R, et al. Guidelines for the Management of Asymptomatic Primary Hyperparathyroidism: Summary Statement from the Fourth International Workshop. J Clin Endocrinol Metab. 2014;99(10):3561-3569. doi: 10.1210/jc.2014-1413.</mixed-citation><mixed-citation xml:lang="en">Bilezikian JP, Brandi ML, Eastell R, et al. Guidelines for the Management of Asymptomatic Primary Hyperparathyroidism: Summary Statement from the Fourth International Workshop. J Clin Endocrinol Metab. 2014;99(10):3561-3569. doi: 10.1210/jc.2014-1413.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Hendrickson CD, Castro Pereira DJ, Comi RJ. Renal Impairment as a Surgical Indication in Primary Hyperparathyroidism: Do the Data Support This Recommendation? J Clin Endocrinol Metab. 2014;99(8):2646-2650. doi: 10.1210/jc.2014-1379.</mixed-citation><mixed-citation xml:lang="en">Hendrickson CD, Castro Pereira DJ, Comi RJ. Renal Impairment as a Surgical Indication in Primary Hyperparathyroidism: Do the Data Support This Recommendation? J Clin Endocrinol Metab. 2014;99(8):2646-2650. doi: 10.1210/jc.2014-1379.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Grube M., Bech JN, Pedersen EB. Primary hyperparathyroidism as a cause of chronic renal failure. Ugeskrift for Laeger. 2012;174(8):502-503.</mixed-citation><mixed-citation xml:lang="en">Grube M., Bech JN, Pedersen EB. Primary hyperparathyroidism as a cause of chronic renal failure. Ugeskrift for Laeger. 2012;174(8):502-503.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
