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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet2015318-24</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-7707</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзор литературы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Сибутрамин: эффективность и безопасность применения в рутинной клинической практике</article-title><trans-title-group xml:lang="en"><trans-title>Sibutramine: efficacy and safety of prescribing in routine clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романцова</surname><given-names>Татьяна Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Romantsova</surname><given-names>Tat'yana Ivanovna</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры эндокринологии</p></bio><bio xml:lang="en"><p>Sc.D., prof.</p></bio><email xlink:type="simple">romantsovatatiana@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО Первый Московский государственный медицинский университет&#13;
им. И.М.Сеченова МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov’s First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2015</year></pub-date><volume>12</volume><issue>3</issue><fpage>18</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Романцова Т.И., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Романцова Т.И.</copyright-holder><copyright-holder xml:lang="en">Romantsova T.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/7707">https://www.omet-endojournals.ru/jour/article/view/7707</self-uri><abstract><p>В мае 2015 г. в Дублине состоялся 17-й Европейский конгресс по эндокринологии. В рамках секции ≪Ожирение≫ были представлены предварительные результаты наблюдательной программы ≪ПримаВера≫ в виде устного доклада. Данная статья представляет собой краткий обзор литературы, отражающий вопросы механизма действия, эффективности и безопасности сибутрамина, а также включает расширенный вариант основных положений доклада.</p></abstract><trans-abstract xml:lang="en"><p>The 17th European Congress of endocrinology was held in Dublin in May 2015. Within the section «Obesity» the preliminary results of the observational program "PRIMAVERA" in the form of an oral report were presented. This article presents a brief review of the literature, reflecting the issues of mechanism of action, efficacy and safety of sibutramine and also includes an extended version of the main provisions of the report.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>энергетический баланс</kwd><kwd>регуляция аппетита</kwd><kwd>моноамины</kwd><kwd>сибутрамин</kwd><kwd>Редуксин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>energy balance</kwd><kwd>appetite regulation</kwd><kwd>monoamines</kwd><kwd>sibutramine</kwd><kwd>Reduxin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. 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