ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/omet2015341-45ometendo-7571Research ArticleЛекцияLectureВлияние сахарного диабета 2 типа и препаратов для его терапии на состояние костной ткани.The effect of type 2 diabetes and its drug therapy on bone quality.ЯлочкинаТатьяна ОлеговнаYalochkinaTat'yana Olegovna

ФГБУ «Эндокринологический научный центр» Минздрава России

PhD student

tatiana540@mail.ruПигароваЕкатерина АлександровнаPigarovaEkaterina Aleksandrovna

к.м.н., ведущий научный сотрудник отделения нейроэндокринологии и остеопатий

PhD,  leading researcher at the Department of Neuroendocrinology and osteopathy

kpigarova@gmail.comФГБУ «Эндокринологический научный центр» Минздрава РоссииРоссияEndocrinology Research CentreRussian Federation2015030820151234145Copyright © Ялочкина Т.О., Пигарова Е.А., 20152015Ялочкина Т.О., Пигарова Е.А.Yalochkina T.O., Pigarova E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/7571

У пациентов с сахарным диабетом 2 типа имеется повышенный риск низкотравматичных переломов. Механизмы, лежащие в основе таких нарушений, в настоящее время окончательно не ясны. Вероятно, к таким изменениям приводят несколько факторов, в частности, повышенный риск падений вследствие осложнений заболевания и нарушение микроархитектоники костной ткани. Использование некоторых групп лекарственных препаратов для лечения сахарного диабета 2 типа также может приводить к повышению риска переломов. 

Individuals with type 2 diabetes have increased risk of fragility fractures. It’s not completely clear by which mechanism type 2 diabetes increases skeletal fragility. A combination of factors, including an increased risk of falling (contributed by complications of the disease) and impaired bone quality apparently leads to a greater fracture risk. Some cl asses of drug therapy for type 2 diabetes may also increase fracture risk by their own mechanism of action.

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The authors declare that there are no conflicts of interest present.