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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet200812-11</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-6838</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Идиопатические отеки: современное состояние проблемы</article-title><trans-title-group xml:lang="en"><trans-title>Idiopathic edema: state of the art</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Pigarova</surname><given-names>E A</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГУ Эндокринологический научный центр Росмедтехнологий</p></bio><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Dzeranova</surname><given-names>L K</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГУ Эндокринологический научный центр Росмедтехнологий</p></bio><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2008</year></pub-date><volume>5</volume><issue>1</issue><issue-title>№1 (2008)</issue-title><fpage>2</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Pigarova E.A., Dzeranova L.K., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Pigarova E.A., Dzeranova L.K.</copyright-holder><copyright-holder xml:lang="en">Pigarova E.A., Dzeranova L.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/6838">https://www.omet-endojournals.ru/jour/article/view/6838</self-uri><abstract><p>В данной статье мы попробуем осветить последние достижения в исследовании такой загадочной проблемы, как идиопатические отеки (ИО), разоблачая наиболее распространенные мифы этого заболевания. Идиопатические отеки - это синдром, заключающийся в избыточной прибавке массы тела, не имею- щей известной причины. Другими терминами для описания данного состояния являются: «циклические и периодические отеки», «синдром задержки жидкости» и «ортостатические отеки».</p></abstract><trans-abstract xml:lang="en"><p>In this article we will try to highlight recent advances in the study of this mysterious problem as idiopathic edema (IE), exposing the most common myths of the disease. Idiopathic edema - a syndrome that is excess weight gain, which has no known cause. Other terms to describe this state is: "cyclic and periodic swelling," "syndrome fluid retention" and "orthostatic edema."</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mach R., Fabre J., Muller A., Neher R., Borth R. Oedeme idiopathique par retention solique avec hyperaldosteronurie. Bull Mem Soc Med Hop. Paris 106:726-732, 1955.</mixed-citation><mixed-citation xml:lang="en">Mach R., Fabre J., Muller A., Neher R., Borth R. Oedeme idiopathique par retention solique avec hyperaldosteronurie. Bull Mem Soc Med Hop. Paris 106:726-732, 1955.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Thorn G. Approach to the patient with «idiopathic oedema» or «periodic swelling».JAMA 206:333-338, 1968.</mixed-citation><mixed-citation xml:lang="en">Thorn G. Approach to the patient with «idiopathic oedema» or «periodic swelling».JAMA 206:333-338, 1968.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">McKendry J.B. Idiopathic oedema. Can Nurse 69:41-43, 1973.</mixed-citation><mixed-citation xml:lang="en">McKendry J.B. Idiopathic oedema. Can Nurse 69:41-43, 1973.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Anand L.C.A., Narula M.A., Anand M.M.M., Mishra L.C.A., Singh C.W. Idiopathic oedema: A missed entity. JAPI 39:258-259, 1991.</mixed-citation><mixed-citation xml:lang="en">Anand L.C.A., Narula M.A., Anand M.M.M., Mishra L.C.A., Singh C.W. Idiopathic oedema: A missed entity. JAPI 39:258-259, 1991.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Denning D.W., Dunnigan M.G., Tillman J., Davis J.A., Forrest C.A. The relationship between “normal” fluid retention in women and idiopathic oedema. Postgrad Med J 66:363-366, 1990.</mixed-citation><mixed-citation xml:lang="en">Denning D.W., Dunnigan M.G., Tillman J., Davis J.A., Forrest C.A. The relationship between “normal” fluid retention in women and idiopathic oedema. Postgrad Med J 66:363-366, 1990.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kay A., Davis C.L. Idiopathic edema. AJKD 34:405-423,1999.</mixed-citation><mixed-citation xml:lang="en">Kay A., Davis C.L. Idiopathic edema. AJKD 34:405-423,1999.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ramanathan M. Idiopathic oedema: a lesson in differential diagnosis. Med J Malaysia 49:285-288, 1994.</mixed-citation><mixed-citation xml:lang="en">Ramanathan M. Idiopathic oedema: a lesson in differential diagnosis. Med J Malaysia 49:285-288, 1994.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Powell A.A., Armstrong M.A. Periferal edema. Am Family Physician 55:1721-1726, 1997.</mixed-citation><mixed-citation xml:lang="en">Powell A.A., Armstrong M.A. Periferal edema. Am Family Physician 55:1721-1726, 1997.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Suzuki H., Fujimaki M., Nakane H., Saito I., Takeshita E., Saruta T. Effect of the angiotensin converting enzyme inhibitor, captopril, on orthostatic sodium and water retention in patients with idiopathic edema. Nephron 39:244-249, 1985.</mixed-citation><mixed-citation xml:lang="en">Suzuki H., Fujimaki M., Nakane H., Saito I., Takeshita E., Saruta T. Effect of the angiotensin converting enzyme inhibitor, captopril, on orthostatic sodium and water retention in patients with idiopathic edema. Nephron 39:244-249, 1985.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Edwards O.M., Bayliss R.I.S. Idiopathic oedema of women. Q J Med 45:125-144, 1976.</mixed-citation><mixed-citation xml:lang="en">Edwards O.M., Bayliss R.I.S. Idiopathic oedema of women. Q J Med 45:125-144, 1976.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Streeten D., Dalakos T., Souma M., Fellerman H., Clift G.V., Schletter F.E., Stevenson C.T., Speller P.J. Studies of the pathogenesis of idiopathic oedema: The roles of postural changes in plasma volume, plasma renin activity, aldosterone secretion rate and glomerular filtration rate in the retention of sodium and water. Clin Sci Mol Med 45:347-373,1973.</mixed-citation><mixed-citation xml:lang="en">Streeten D., Dalakos T., Souma M., Fellerman H., Clift G.V., Schletter F.E., Stevenson C.T., Speller P.J. Studies of the pathogenesis of idiopathic oedema: The roles of postural changes in plasma volume, plasma renin activity, aldosterone secretion rate and glomerular filtration rate in the retention of sodium and water. Clin Sci Mol Med 45:347-373,1973.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Thibonnier M., Marchetti J., Corvol P., Menard J., Sire O., Milliez P. Influence of previous diuretic intake on the humoral and hormonal profile of idiopathic oede- ma. Eur J Clin Invest 11:19-24, 1981.</mixed-citation><mixed-citation xml:lang="en">Thibonnier M., Marchetti J., Corvol P., Menard J., Sire O., Milliez P. Influence of previous diuretic intake on the humoral and hormonal profile of idiopathic oede- ma. Eur J Clin Invest 11:19-24, 1981.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Streeten D., Speller P. The role of aldosterone and vasopressin in the postural changes in renal excretion in normal subjects and patients with idiopathic edema. Metabolism 15:53-64, 1966.</mixed-citation><mixed-citation xml:lang="en">Streeten D., Speller P. The role of aldosterone and vasopressin in the postural changes in renal excretion in normal subjects and patients with idiopathic edema. Metabolism 15:53-64, 1966.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Ishimura E., Nishigava Y., Morita A., Yoshida H.I., Nishio M., Morii H. Water loading tests both in supine and upright positions in three cases of idiopathic oedema. Osaka City Med J 37: 141-148, 1991.</mixed-citation><mixed-citation xml:lang="en">Ishimura E., Nishigava Y., Morita A., Yoshida H.I., Nishio M., Morii H. Water loading tests both in supine and upright positions in three cases of idiopathic oedema. Osaka City Med J 37: 141-148, 1991.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Verbalis J. The syndrome of inappropriate antidiuretic hormone excretion and other hyperosmolar disorders. Boston, MA, Little, Brown, 1997.</mixed-citation><mixed-citation xml:lang="en">Verbalis J. The syndrome of inappropriate antidiuretic hormone excretion and other hyperosmolar disorders. Boston, MA, Little, Brown, 1997.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">De Bold A. Atrial natriuretic factor: An overview. Fed Proc 45:2081-2085, 1986.</mixed-citation><mixed-citation xml:lang="en">De Bold A. Atrial natriuretic factor: An overview. Fed Proc 45:2081-2085, 1986.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Loutzenhiser R., Hayashi K., Epstein M. Atrial natriuretic peptide reverses afferent arteriolar vasoconstriction and potentiates efferent arteriolar vasoconstrictionin the isolated perfused rat kidney. J Pharmacol Exp Ther 246:522-528, 1988.</mixed-citation><mixed-citation xml:lang="en">Loutzenhiser R., Hayashi K., Epstein M. Atrial natriuretic peptide reverses afferent arteriolar vasoconstriction and potentiates efferent arteriolar vasoconstrictionin the isolated perfused rat kidney. J Pharmacol Exp Ther 246:522-528, 1988.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Solomon L., Atherton J., Bobinski H., Green R. Effect of posture on plasma immunoreactine atrial natriuretic peptide concentrations in man. Clin Sci 71:299- 305, 1986.</mixed-citation><mixed-citation xml:lang="en">Solomon L., Atherton J., Bobinski H., Green R. Effect of posture on plasma immunoreactine atrial natriuretic peptide concentrations in man. Clin Sci 71:299- 305, 1986.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson G. Jr., Streeten D. The role of posture on plasma atrial natriuretic hormone and renal function during salt loading in patients with and without postural (idiopathic) edema. J Clin Endicrinol Metab 71:243-246, 1990.</mixed-citation><mixed-citation xml:lang="en">Anderson G. Jr., Streeten D. The role of posture on plasma atrial natriuretic hormone and renal function during salt loading in patients with and without postural (idiopathic) edema. J Clin Endicrinol Metab 71:243-246, 1990.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Young J.B., Brownjohn A.M., Chapman C., Lee M.R. Evidence for a hypothalam- ic disturbance in cyclical oedema. Br Med J 286:1691-1693, 1983.</mixed-citation><mixed-citation xml:lang="en">Young J.B., Brownjohn A.M., Chapman C., Lee M.R. Evidence for a hypothalam- ic disturbance in cyclical oedema. Br Med J 286:1691-1693, 1983.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Mills D., Buckman M., Peake G. Effects of prolactin administration and supression on blood pressure and body fluid compartments in the rat. Endocrinology 109:1590-1596, 1982.</mixed-citation><mixed-citation xml:lang="en">Mills D., Buckman M., Peake G. Effects of prolactin administration and supression on blood pressure and body fluid compartments in the rat. Endocrinology 109:1590-1596, 1982.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Wortsman J., Singh K., Murphy J. Evidence for the hypothalamic origin of the polycystic ovary syndrome. Obstet Gynecol 58:137-141, 1981.</mixed-citation><mixed-citation xml:lang="en">Wortsman J., Singh K., Murphy J. Evidence for the hypothalamic origin of the polycystic ovary syndrome. Obstet Gynecol 58:137-141, 1981.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ettigi P., Brown G. Psychoneuroendocrinology of affective disorder: An overview. Am J Psychiatry 134:493-501, 1977.</mixed-citation><mixed-citation xml:lang="en">Ettigi P., Brown G. Psychoneuroendocrinology of affective disorder: An overview. Am J Psychiatry 134:493-501, 1977.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Lewallen C., Rall J., Berman M. Studies of the iodoalbumin metabolism. II. The effects of thyroid hormone. J Clin Invest 38:88-101, 1979.</mixed-citation><mixed-citation xml:lang="en">Lewallen C., Rall J., Berman M. Studies of the iodoalbumin metabolism. II. The effects of thyroid hormone. J Clin Invest 38:88-101, 1979.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Khader A., Aber G. The relationship between the «idiopathic edema syndrome» and subclinical hypothyroidism. Clin Endocrinol 10:271-279, 1979.</mixed-citation><mixed-citation xml:lang="en">Al-Khader A., Aber G. The relationship between the «idiopathic edema syndrome» and subclinical hypothyroidism. Clin Endocrinol 10:271-279, 1979.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Streeten D. Orthostatic disorders of the sirculation: mechanisms, manifestations and treatment (chapt 3). New York, NY, Plenum, 1987, p. 73.</mixed-citation><mixed-citation xml:lang="en">Streeten D. Orthostatic disorders of the sirculation: mechanisms, manifestations and treatment (chapt 3). New York, NY, Plenum, 1987, p. 73.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Jeffcoate W.J., Davis J.R.E. Cyclical oedema. Br Med J 287:211-213, 1983.</mixed-citation><mixed-citation xml:lang="en">Jeffcoate W.J., Davis J.R.E. Cyclical oedema. Br Med J 287:211-213, 1983.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Czapla K., Farish E., Hayenes E.C.M., Henderson J.B., Pelosi A.J., Dunnigan M.G. Thyroid function in idiopathic oedema. Clin Endocrinol 45:467-470, 1996.</mixed-citation><mixed-citation xml:lang="en">Czapla K., Farish E., Hayenes E.C.M., Henderson J.B., Pelosi A.J., Dunnigan M.G. Thyroid function in idiopathic oedema. Clin Endocrinol 45:467-470, 1996.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">McDonald R., Goldber L., McNay J., Tuttle E. Effects of dopamine in man: Augmentation of sodium excretion, glomerular filtration rate, and renal plasma flow. J Clin Invest 43:1116-1124, 1964.</mixed-citation><mixed-citation xml:lang="en">McDonald R., Goldber L., McNay J., Tuttle E. Effects of dopamine in man: Augmentation of sodium excretion, glomerular filtration rate, and renal plasma flow. J Clin Invest 43:1116-1124, 1964.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Sowers J., Sollars E., Tuck M., Asp N. Dopaminergic modulation of renin activity and aldosterone and prolactin secretion in the spontaneously hypertensive rat. Proc Soc Exp Biol Med 164:598-603, 1980.</mixed-citation><mixed-citation xml:lang="en">Sowers J., Sollars E., Tuck M., Asp N. Dopaminergic modulation of renin activity and aldosterone and prolactin secretion in the spontaneously hypertensive rat. Proc Soc Exp Biol Med 164:598-603, 1980.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Kuchel O., Cuche J.L., Buu N.T., Guuthrie G.P., Unger T. et al. Catecholamine excretion in «idiopathic» edema: Decreased dopamine excretion, a pathogenic fac- tor? J Clin Endocrinol Metab 44:639-646, 1977.</mixed-citation><mixed-citation xml:lang="en">Kuchel O., Cuche J.L., Buu N.T., Guuthrie G.P., Unger T. et al. Catecholamine excretion in «idiopathic» edema: Decreased dopamine excretion, a pathogenic fac- tor? J Clin Endocrinol Metab 44:639-646, 1977.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Everred D., Horrobin O.M., Vice P., Cole E., Nassar B. Idiopathic oedema and prolactin. Proc R Soc Med 69:427-428, 1976.</mixed-citation><mixed-citation xml:lang="en">Everred D., Horrobin O.M., Vice P., Cole E., Nassar B. Idiopathic oedema and prolactin. Proc R Soc Med 69:427-428, 1976.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Dent R.G., Edwards O.M. Idiopathic oedema: A study of the effects of bromocriptine. Clin Endocrinol 11:75-80, 1979.</mixed-citation><mixed-citation xml:lang="en">Dent R.G., Edwards O.M. Idiopathic oedema: A study of the effects of bromocriptine. Clin Endocrinol 11:75-80, 1979.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Norbiato G., Bevilacqua M., Raggi U., Micossi P., Nitti F., Lanfredini M., Barbieri S. Effect of metoclopramide, a dopaminergic inhibitor, on renin and aldosterone in idiopathicedema: Possible therapeutic approach with levodopa and carbidopa. J Clin Endocrinol Metab 48:37-42, 1979.</mixed-citation><mixed-citation xml:lang="en">Norbiato G., Bevilacqua M., Raggi U., Micossi P., Nitti F., Lanfredini M., Barbieri S. Effect of metoclopramide, a dopaminergic inhibitor, on renin and aldosterone in idiopathicedema: Possible therapeutic approach with levodopa and carbidopa. J Clin Endocrinol Metab 48:37-42, 1979.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Iimura O. The role of renal dopaminergic activity in the pathophysiology of essencial hypertension. Jpn Heart J 37:815-828, 1996.</mixed-citation><mixed-citation xml:lang="en">Iimura O. The role of renal dopaminergic activity in the pathophysiology of essencial hypertension. Jpn Heart J 37:815-828, 1996.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Cheng H.F., Becker B.N., Harris R.C. Dopamine decreases expression of type-1 angiotensinII receptors in renal proximal tubule. J Clin Invest 97:2745-2752, 1996.</mixed-citation><mixed-citation xml:lang="en">Cheng H.F., Becker B.N., Harris R.C. Dopamine decreases expression of type-1 angiotensinII receptors in renal proximal tubule. J Clin Invest 97:2745-2752, 1996.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Z.Q., Siragy H.M., Felder R.A., Carey R.M. Intrarenal dopamine production and distribution in the rat: Physiological control of sodium excretion. Hypertention. 29:228-234, 1997.</mixed-citation><mixed-citation xml:lang="en">Wang Z.Q., Siragy H.M., Felder R.A., Carey R.M. Intrarenal dopamine production and distribution in the rat: Physiological control of sodium excretion. Hypertention. 29:228-234, 1997.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Chatziantoniou C., Ruan X., Arendshorst W.T. Defective G protein activation of the cAMP pathway in the rat kidney during genetic hypertention. Proc atl Acad Sci USA 92:2924-2928, 1995.</mixed-citation><mixed-citation xml:lang="en">Chatziantoniou C., Ruan X., Arendshorst W.T. Defective G protein activation of the cAMP pathway in the rat kidney during genetic hypertention. Proc atl Acad Sci USA 92:2924-2928, 1995.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Valensi P., Behar A. Clinical implications of impaired microcirculation. Int Angiol 14:26-31, 1995.</mixed-citation><mixed-citation xml:lang="en">Valensi P., Behar A. Clinical implications of impaired microcirculation. Int Angiol 14:26-31, 1995.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Coleman M., Horwith M., Brown J. Idiopathic edema, studies demonstrationg protein-leaking angiopathy. Am J Med 49:106-113,1970.</mixed-citation><mixed-citation xml:lang="en">Coleman M., Horwith M., Brown J. Idiopathic edema, studies demonstrationg protein-leaking angiopathy. Am J Med 49:106-113,1970.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Gonzales-Argulo A., Frazer A., Mintz G. Submicroscopic alterations in capillaries of sceletal muscles by polymyositis. Am J Med 45:873-879, 1968.</mixed-citation><mixed-citation xml:lang="en">Gonzales-Argulo A., Frazer A., Mintz G. Submicroscopic alterations in capillaries of sceletal muscles by polymyositis. Am J Med 45:873-879, 1968.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Sims E., MacKay B., Shirai T. The relation of capillary angiopathy and diabetes mellitus to idiopathic edema. Ann Intern Med 63:972-987, 1965.</mixed-citation><mixed-citation xml:lang="en">Sims E., MacKay B., Shirai T. The relation of capillary angiopathy and diabetes mellitus to idiopathic edema. Ann Intern Med 63:972-987, 1965.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Williams S., Rayman G., Took J. Dependent oedema and attenuation of postural vasoconstriction assosiated with nifedipine therapy for hypertension in diabetic patients. Eur J Clin Pharmacol 37:333-335, 1989.</mixed-citation><mixed-citation xml:lang="en">Williams S., Rayman G., Took J. Dependent oedema and attenuation of postural vasoconstriction assosiated with nifedipine therapy for hypertension in diabetic patients. Eur J Clin Pharmacol 37:333-335, 1989.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">De Wardener H.E. Idiopathic edema: role of diuretic abuse. Kidney Int 19:881-892, 1981.</mixed-citation><mixed-citation xml:lang="en">De Wardener H.E. Idiopathic edema: role of diuretic abuse. Kidney Int 19:881-892, 1981.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Fairburn C. Binge-Eating and bulimia revised. London, England, Smith, Kline, and French, 1982.</mixed-citation><mixed-citation xml:lang="en">Fairburn C. Binge-Eating and bulimia revised. London, England, Smith, Kline, and French, 1982.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Bihum J.A.P., McSherry J., Marciano D. Idiopathic edema and eating disorders: Evidence for an association. Int I Eat Disord 14: 197-201, 1993.</mixed-citation><mixed-citation xml:lang="en">Bihum J.A.P., McSherry J., Marciano D. Idiopathic edema and eating disorders: Evidence for an association. Int I Eat Disord 14: 197-201, 1993.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Gamble J., Ross G., Tisdall F. The metabolism of fixed base during fasting. J Biol Chem 57:633-695, 1923.</mixed-citation><mixed-citation xml:lang="en">Gamble J., Ross G., Tisdall F. The metabolism of fixed base during fasting. J Biol Chem 57:633-695, 1923.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Veverbrants E., Arky R.A. Effects of fasting and refeeding. I. Studies on sodium, potassium and water excretion on a constant electrolyte and fluid intake. J Clin Endocrinol 29:55-62, 1969.</mixed-citation><mixed-citation xml:lang="en">Veverbrants E., Arky R.A. Effects of fasting and refeeding. I. Studies on sodium, potassium and water excretion on a constant electrolyte and fluid intake. J Clin Endocrinol 29:55-62, 1969.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">DeFronzo R., Cooke C., Andres R., Faloona G., Davis P: The effect of insulin on renal handling of sodium, potasium, calcium, and phosphate in man. J Clin Invest 55:845-855, 1975.</mixed-citation><mixed-citation xml:lang="en">DeFronzo R., Cooke C., Andres R., Faloona G., Davis P: The effect of insulin on renal handling of sodium, potasium, calcium, and phosphate in man. J Clin Invest 55:845-855, 1975.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Landsberg L., Young J. Fasting, refeeding, and regulation of the sympathetic nervous system. N Eng I Med 298:1295-1301, 1978.</mixed-citation><mixed-citation xml:lang="en">Landsberg L., Young J. Fasting, refeeding, and regulation of the sympathetic nervous system. N Eng I Med 298:1295-1301, 1978.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Dalakos T., Streeten D. The role of the plasma volume in the increase of aldosterone secretion rate during sodium deprivation. Clin Sci Med 48:161-165, 1975.</mixed-citation><mixed-citation xml:lang="en">Dalakos T., Streeten D. The role of the plasma volume in the increase of aldosterone secretion rate during sodium deprivation. Clin Sci Med 48:161-165, 1975.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">McGregor G.A., Markandu N.D., Roolston J.E., Jones J.C., de Wardener H.E. Is «idiopathic» oedema idiopathic? Lancet 1: 397-400, 1979.</mixed-citation><mixed-citation xml:lang="en">McGregor G.A., Markandu N.D., Roolston J.E., Jones J.C., de Wardener H.E. Is «idiopathic» oedema idiopathic? Lancet 1: 397-400, 1979.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Эгарт Ф.М., Атаманова Т.М. Синдром идиопатических отеков у женщин. // Советская медицина 1983. - N6. - C.31-35, 1983.</mixed-citation><mixed-citation xml:lang="en">Эгарт Ф.М., Атаманова Т.М. Синдром идиопатических отеков у женщин. // Советская медицина 1983. - N6. - C.31-35, 1983.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Старкова Н.Т., Эгарт Ф.М., Атаманова Т.М. Фармакотерапия синдрома идиопатических отеков. // Внутренние болезни. - 1982. - Т.21. - №6. - С.78-81б.</mixed-citation><mixed-citation xml:lang="en">Старкова Н.Т., Эгарт Ф.М., Атаманова Т.М. Фармакотерапия синдрома идиопатических отеков. // Внутренние болезни. - 1982. - Т.21. - №6. - С.78-81б.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
