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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet2014148-52</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-6660</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Персонализированное лечение ожирения, осложненного синдромом обструктивного апноэ сна</article-title><trans-title-group xml:lang="en"><trans-title>Personalized treatment of obesity complicated with obstructive sleep apnea syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Strueva</surname><given-names>N V</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отделения терапии эндокринопатий лечебно-диагностического отдела; ФГБУ «Эндокринологический научный центр» Минздрава России</p></bio><email xlink:type="simple">nstr84@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Saveleva</surname><given-names>L V</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., зав. отделением терапии эндокринопатий лечебно-диагностического отдела; ФГБУ «Эндокринологический научный центр» Минздрава России</p></bio><email xlink:type="simple">slv63@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Melnichenko</surname><given-names>G A</given-names></name></name-alternatives><bio xml:lang="ru"><p>акад., проф., д.м.н., директор Института клинической эндокринологии; ФГБУ «Эндокринологический научный центр» Минздрава России</p></bio><email xlink:type="simple">melnich@endocrincentr.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Poluektov</surname><given-names>M G</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н, доцент кафедры нервных болезней; ГБOУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» МЗ РФ</p></bio><email xlink:type="simple">polouekt@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Gegel</surname><given-names>N V</given-names></name></name-alternatives><bio xml:lang="ru"><p>м.н.с.; ФГБУ «Московский научно-исследовательский институт психиатрии» МЗ РФ</p></bio><email xlink:type="simple">socute2006@rambler.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2014</year></pub-date><volume>11</volume><issue>1</issue><issue-title>№1 (2014)</issue-title><fpage>48</fpage><lpage>52</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Strueva N.V., Saveleva L.V., Melnichenko G.A., Poluektov M.G., Gegel N.V., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Strueva N.V., Saveleva L.V., Melnichenko G.A., Poluektov M.G., Gegel N.V.</copyright-holder><copyright-holder xml:lang="en">Strueva N.V., Saveleva L.V., Melnichenko G.A., Poluektov M.G., Gegel N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/6660">https://www.omet-endojournals.ru/jour/article/view/6660</self-uri><abstract><p>Синдром обструктивного апноэ во сне (СОАС) и ожирение - это многофакторные и взаимоотягощающие заболевания. Снижение массы тела оказывается достаточно эффективным в отношении контроля нарушений дыхания во время сна, но влияние лечения СОАС на динамику массы тела у больных ожирением остается малоизученным. Особенностью представленного клинического случая является клинически значимое снижение массы тела у пациента с морбидным ожирением, осложненным синдромом обструктивного апноэ во сне тяжелой степени при применении стандартного подхода к терапии ожирения. Снижение массы тела в данном случае было достигнуто благодаря высокой приверженности пациента к терапии и отсутствию сопутствующих психических расстройств. Высокая стоимость приборов СиПАП-терапии, постоянное использование их во время ночного сна и необходимость титрации терапевтического давления делает данную терапию малодоступной. В связи с чем в комплексном лечении ожирения у пациентов с нарушениями дыхания во сне при отсутствии возможности проведения СиПАП-терапии следует предусмотреть индивидуальное терапевтическое обучение для повышения их медицинской мотивации и комплаентности, более частые визиты к эндокринологу, а также коррекцию сопутствующих психопатологических нарушений для достижения эффективного и долгосрочного терапевтического успеха.</p></abstract><trans-abstract xml:lang="en"><p>Obstructive sleep apnea (OSA) and obesity are mutually burdening clinical conditions. Weight loss is quite effective for the control of breathing disorders during sleep, but the impact of OSA treatment on the dynamics of body weight in obese patients remains poorly studied. Presented clinical case features a significant reduction in body weight in a patient with morbid obesity complicated by severe OSA with contemporary approach and without CPAP therapy due to high patient adherence to therapy and absence of comorbidities.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>синдром обструктивного апноэ сна</kwd><kwd>СиПАП-терапия</kwd><kwd>комплаентность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>obstructive sleep apnea</kwd><kwd>continuous positive airway pressure</kwd><kwd>CPAP</kwd><kwd>weight loss</kwd><kwd>compliance</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бузунов Р. В. Синдром обструктивного апноэ сна в сочетании с ожирением: особенности патогенеза, диагностики и лечения. Автореферат диссертации док. мед. наук, 2003.</mixed-citation><mixed-citation xml:lang="en">Бузунов Р. В. 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