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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet2012233-42</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-6543</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Витамин D и метаболизм: факты, мифы и предубеждения</article-title><trans-title-group xml:lang="en"><trans-title>Vitamin D and metabolism: facts, myths and misconceptions</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плещева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Plescheva</surname><given-names>A V</given-names></name></name-alternatives><email xlink:type="simple">nastia040883@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пигарова</surname><given-names>Екатерина Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Pigarova</surname><given-names>E A</given-names></name></name-alternatives><email xlink:type="simple">kpigarova@gmail.com</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дзеранова</surname><given-names>Лариса Константиновна</given-names></name><name name-style="western" xml:lang="en"><surname>Dzeranova</surname><given-names>L K</given-names></name></name-alternatives><email xlink:type="simple">metabol@endocrincentr.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2012</year></pub-date><volume>9</volume><issue>2</issue><issue-title>№2 (2012)</issue-title><fpage>33</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Плещева А.В., Пигарова Е.А., Дзеранова Л.К., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Плещева А.В., Пигарова Е.А., Дзеранова Л.К.</copyright-holder><copyright-holder xml:lang="en">Plescheva A.V., Pigarova E.A., Dzeranova L.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/6543">https://www.omet-endojournals.ru/jour/article/view/6543</self-uri><abstract><p>Витамин D необходим для широкого спектра физиологических процессов и оптимального состояния здоровья. В детстве и юности адекватные уровни витамина D нужны для обеспечения роста клеток, формирования скелета и роста. Витамин D является жирорастворимым витамином, который содержится в очень немногих продуктах питания. Основным источником его являются обогащенные продукты и биологически активные добавки к пище. Витамин D вырабатывается в организме, когда ультрафиолетовое излучение попадает на кожу. Адекватное потребление и статус витамина D во многом зависят от возраста, сопутствующих заболеваний и использования некоторых лекарственных препаратов и подробно освещены в данной статье. Последние эпидемиологические и экспериментальные данные показали, что низкий уровень витамина D тесно связан с уровнем общей смертности, сердечно-сосудистыми и онкологическими заболеваниями (в основном молочной железы, простаты и толстого кишечника), артериальной гипертензией, метаболическим синдромом, сахарным диабетом 1 и 2 типов. Тем не менее, данные, подтверждающие защитный эффект витамина D помимо заболеваний костной ткани, таких как рахит, остеопороз и остеомаляция, не обладают высокой достоверностью, поэтому только проводимые в настоящее время крупные контролируемые клинические испытания позволят дать ответы на эти вопросы.</p></abstract><trans-abstract xml:lang="en"><p>Vitamin D is essential for a vast number of physiologic processes, and thus adequate levels are necessary for optimal health. During childhood and adolescence, an adequate vitamin D status is needed due to its important role in cell growth, skeletal development and growth. Vitamin D is a fat-soluble vitamin that is naturally found in very few foods, is added to others, and is available as a dietary supplement. It is produced endogenously when ultraviolet light strikes the skin. The adequate intake and status of vitamin D greatly depends on age, concomitant diseases and the use of some medications that are covered in-depth in the article. Recent epidemiologic and experimental evidence has suggested that low vitamin D concentrations seem to be significantly associated with all-cause mortality, cardiovascular disease, cancer (mainly breast, prostate and colorectal), hypertension, metabolic syndrome, diabetes mellitus type 1 and type 2. However, the data supporting protective effects of vitamin D supplementation on conditions other than skeletal diseases like rickets, osteoporosis and osteomalacia are very weak, and the large, controlled clinical trials that are in progress now should resolve this issue.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дефицит витамина D</kwd><kwd>колекальциферол</kwd><kwd>остеопороз</kwd><kwd>онкологические заболевания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>25(OH)D</kwd><kwd>vitamin D deficiency</kwd><kwd>25(OH)D</kwd><kwd>cholecalciferol</kwd><kwd>osteoporosis</kwd><kwd>cancer</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Calcium and Vitamin D. 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