References

ometendo

Ожирение и метаболизм

Obesity and metabolism

2071-87132306-5524

Endocrinology Research Centre

10.14341/omet201343-9

ometendo-6383

Research Article

Статьи

Articles

«Парадокс ожирения» – еще один взгляд на проблему сердечно-сосудистых заболеваний

Obesity Paradox" – another look at the problem of cardiovascular disease

Shpagina

O V

Bondarenko

I Z

д.м.н, гл.н.с. отделения кардиологии

iz_bondarenko@mail.ru

2013

15122013

104

№4 (2013)

2013

Shpagina O.V., Bondarenko I.Z.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.omet-endojournals.ru/jour/article/view/6383

Крупные эпидемиологические исследования прошлого века продемонстрировали, что последствием ожирения являются такие тяжелые заболевания, как сахарный диабет, артериальная гипертония, ишемическая болезнь сердца, хроническая сердечная недостаточность, нарушения мозгового кровообращения. В развитых странах сердечно-сосудистые заболевания стали лидирующей причиной смертности. За последние 5–6 лет появились сведения о том, что люди с избыточной массой тела и ожирением I степени имеют более высокую продолжительность жизни, чем лица с нормальным весом. В 2009 году опубликованы данные о том, у пациентов с хронической сердечной недостаточности наличие ожирения не ухудшает сердечно-сосудистый прогноз: избыточная масса тела коррелирует с уменьшением общей смертности на 25%, а при ожирении I степени риск смерти снижается на 12%. Этот феномен получил название «парадокса ожирения», причины которого рассмотрены в данном обзоре.

Major epidemiologic studies over the last century demonstrated that obesity leads to several severe diseases such as diabetes mellitus, hypertension, coronary heart disease, chronic heart failure, cerebrovascular accidents. In developed countries cardiovascular diseases became the main cause of death. In the last 5–6 years some studies showed that people with overweight and obesity of the first degree have a higher life expectancy than people with normal weight. In 2009, the published data showed that the presence of obesity in patients with chronic heart failure does not impair cardiovascular prognosis. Overweight correlates with a decrease in overall mortality by 25%. And in a first degree of obesity the risk of death is reduced by 12%. This phenomenon is called "obesity paradox" and the causes of which are discussed in this review.

парадокс ожиренияжировая тканьишемическая болезнь сердцахроническая сердечная недостаточность

obesity paradoxadipose tissuechronic heart failurecoronary heart disease

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The authors declare that there are no conflicts of interest present.