ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/2071-8713-5329ometendo-5329Research ArticleСтатьиArticlesЗаместительная гормональная терапия у женщин в постменопаузе: современные тенденцииZamestitel'naya gormonal'naya terapiya u zhenshchin v postmenopauze: sovremennye tendentsiiChebotnikovaT V-Mel'nichenkoG A-DavydovaG N-20081509200853№3 (2008)26Copyright © Chebotnikova T.V., Mel'nichenko G.A., Davydova G.N., 20082008Chebotnikova T.V., Mel'nichenko G.A., Davydova G.N.Chebotnikova T.V., Mel'nichenko G.A., Davydova G.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/5329ReferencesСметник В.П., Кулаков В.И. (ред.) Руководство по климактерию. М: Медицинское информационное агентство 2001.Сметник В.П., Кулаков В.И. (ред.) Руководство по климактерию. М: Медицинское информационное агентство 2001.Чеботникова Т.В., Мельниченко Г.А., Андреева Е.Н. // Проблемы репродукции № 2. 2004. с. 69-76.Чеботникова Т.В., Мельниченко Г.А., Андреева Е.Н. // Проблемы репродукции № 2. 2004. с. 69-76.Йен С.С.К. - Репродуктивная эндокринология. - 1998.Йен С.С.К. - Репродуктивная эндокринология. - 1998.Hu F.B., Grodstein F., Hennekens C.H. Age at natural menopause and risk of cardiovascular disease. / Arch Intern Med, 1999; 159(10): 1061-6.Hu F.B., Grodstein F., Hennekens C.H. Age at natural menopause and risk of cardiovascular disease. / Arch Intern Med, 1999; 159(10): 1061-6.Skouby S.O., Al-Azzawi F., Barlow D. // Climacteric medicine: European Menopause and Andropause Society (EMAS) 2004/2005 position statements on peri- and postmenopausal hormone replacement therapy. Maturitas. 2005 May 16; 51(1): 8-14.Skouby S.O., Al-Azzawi F., Barlow D. // Climacteric medicine: European Menopause and Andropause Society (EMAS) 2004/2005 position statements on peri- and postmenopausal hormone replacement therapy. Maturitas. 2005 May 16; 51(1): 8-14.Hersh A.L., Stefanick M.L., Stafford R.S. National use of postmenopausal hormone therapy: annual trends and response to recent evidence. JAMA. 2004; 291: 47-53.Hersh A.L., Stefanick M.L., Stafford R.S. National use of postmenopausal hormone therapy: annual trends and response to recent evidence. JAMA. 2004; 291: 47-53.Strothmann A., Schneider H.P. Hormone therapy: the European women's perspective. Climacteric. 2003; 6: 337-346.Strothmann A., Schneider H.P. Hormone therapy: the European women's perspective. Climacteric. 2003; 6: 337-346.Warming L., Ravn P., Nielsen T. Safety and efficacy of drospirenone used in a continuous combination with 17beta-estradiol for prevention of postmenopausal osteoporosis. Climacteric. 2004 Mar; 7(1): 103-11.Warming L., Ravn P., Nielsen T. Safety and efficacy of drospirenone used in a continuous combination with 17beta-estradiol for prevention of postmenopausal osteoporosis. Climacteric. 2004 Mar; 7(1): 103-11.British Menopause Society Council Consensus Statement, 2007British Menopause Society Council Consensus Statement, 2007Gold E.B., Colvin A., Avis N. Longitudinal analysis of the association between vaso-motor symptoms and race/ethnicity across the menopausal transition: study of women's health across the nation. Am J Public Health. 2006 Jul; 96(7): 1226-35.Gold E.B., Colvin A., Avis N. Longitudinal analysis of the association between vaso-motor symptoms and race/ethnicity across the menopausal transition: study of women's health across the nation. Am J Public Health. 2006 Jul; 96(7): 1226-35.Loprinzi C.L., Barton D.L., Rhodes D. Lancet Oncol. 2001; 2: 199-204. Management of hot flashes in breast-cancer survivors.Loprinzi C.L., Barton D.L., Rhodes D. Lancet Oncol. 2001; 2: 199-204. Management of hot flashes in breast-cancer survivors.Gold E.B., Bair Y., Zhang G. Cross-sectional analysis of specific complementary and alternative medicine (CAM) use by racial/ethnic group and menopausal status: the Study of Women's Health Across the Nation (SWAN). Menopause. 2007 Jul-Aug; 14(4): 612-23Gold E.B., Bair Y., Zhang G. Cross-sectional analysis of specific complementary and alternative medicine (CAM) use by racial/ethnic group and menopausal status: the Study of Women's Health Across the Nation (SWAN). Menopause. 2007 Jul-Aug; 14(4): 612-23National Institutes of Health. National Institutes of Health State-of-the-Science Conference statement: management of menopause-related symptoms. Ann Intern Med. 2005;142:1003-1013.National Institutes of Health. National Institutes of Health State-of-the-Science Conference statement: management of menopause-related symptoms. Ann Intern Med. 2005;142:1003-1013.Avis N.E., Brambilla D., McKinlay S.M., Vass K. A longitudinal analysis of the association between menopause and depression. Results from the Massachusetts Women's Health Study. Ann Epidemiol. 1994; 4: 214-220.Avis N.E., Brambilla D., McKinlay S.M., Vass K. A longitudinal analysis of the association between menopause and depression. Results from the Massachusetts Women's Health Study. Ann Epidemiol. 1994; 4: 214-220.Sherwin B.B. Hormones, mood, and cognitive functioning in postmenopausal women. Obstet Gynecol. 1996; 87(suppl): 20S-26S.Sherwin B.B. Hormones, mood, and cognitive functioning in postmenopausal women. Obstet Gynecol. 1996; 87(suppl): 20S-26S.Dennerstein L. Well being, symptoms and the menopausal transition. Maturitas. 1996; 23: 147-157.Dennerstein L. Well being, symptoms and the menopausal transition. Maturitas. 1996; 23: 147-157.Schmidt P.J., Nieman L., Danaceau M.A., et al. Estrogen replacement in perimenopause-related depression: a preliminary report. Am J Obstet Gynecol. 2000;183:414-420.Schmidt P.J., Nieman L., Danaceau M.A., et al. Estrogen replacement in perimenopause-related depression: a preliminary report. Am J Obstet Gynecol. 2000;183:414-420.Soares C.N., Almeida O.P., Joffe H., Cohen L.S. Efficacy of estradiol for the treatment of depressive disorders in perimenopausal women: a double-blind, randomized, placebo-controlled trial. Arch Gen Psychiatry. 2001;58:529-534.Soares C.N., Almeida O.P., Joffe H., Cohen L.S. Efficacy of estradiol for the treatment of depressive disorders in perimenopausal women: a double-blind, randomized, placebo-controlled trial. Arch Gen Psychiatry. 2001;58:529-534.Dennerstein L., Dudley E.C., Hopper J.L., Guthrie J.R., Burger H.G. A prospective population-based study of menopausal symptoms. Obstet Gynecol. 2000; 96: 351-358.Dennerstein L., Dudley E.C., Hopper J.L., Guthrie J.R., Burger H.G. A prospective population-based study of menopausal symptoms. Obstet Gynecol. 2000; 96: 351-358.Kovalevsky G. Female sexual dysfunction and use of hormone therapy in postmenopausal women. Semin Reprod Med. 2005;23:180-187.Kovalevsky G. Female sexual dysfunction and use of hormone therapy in postmenopausal women. Semin Reprod Med. 2005;23:180-187.Ponzone R., Biglia N., Jacomuzzi M.E., Maggiorotto F., Mariani L., Sismondi P. Vaginal oestrogen therapy after breast cancer: is it safe? Eur J Cancer. 2005;41:2673-2681.Ponzone R., Biglia N., Jacomuzzi M.E., Maggiorotto F., Mariani L., Sismondi P. Vaginal oestrogen therapy after breast cancer: is it safe? Eur J Cancer. 2005;41:2673-2681.Fantl J.A., Cardozo L., McClish D.K. Estrogen therapy in the management of urinary incontinence in postmenopausal women: a meta-analysis. First report of the Hormones and Urogenital Therapy Committee. Obstet Gynecol. 1994;83:12-18.Fantl J.A., Cardozo L., McClish D.K. Estrogen therapy in the management of urinary incontinence in postmenopausal women: a meta-analysis. First report of the Hormones and Urogenital Therapy Committee. Obstet Gynecol. 1994;83:12-18.Grady D., Brown J.S., Vittinghoff E., et al. Postmenopausal hormones and incontinence: the Heart and Estrogen/Progestin Replacement Study. Obstet Gynecol. 2001; 97: 116-120.Grady D., Brown J.S., Vittinghoff E., et al. Postmenopausal hormones and incontinence: the Heart and Estrogen/Progestin Replacement Study. Obstet Gynecol. 2001; 97: 116-120.Lobo R.A. The rationale for low-dose hormonal therapy. Endocrine. 2004; 24: 217-221.Lobo R.A. The rationale for low-dose hormonal therapy. Endocrine. 2004; 24: 217-221.Grodstein F., Manson J.E., Colditz G.A., Willett W.C., Speizer F.E., Stampfer M.J. A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med. 2000; 133: 933-941.Grodstein F., Manson J.E., Colditz G.A., Willett W.C., Speizer F.E., Stampfer M.J. A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med. 2000; 133: 933-941.Strothmann A., Schneider H.P. Hormone therapy: the European women's perspective. Climacteric. 2003; 6: 337-346.Strothmann A., Schneider H.P. Hormone therapy: the European women's perspective. Climacteric. 2003; 6: 337-346.Chlebowski R.T., Hendrix S.L., Langer R.D., et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. JAMA. 2003; 289: 3243-3253.Chlebowski R.T., Hendrix S.L., Langer R.D., et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. JAMA. 2003; 289: 3243-3253.Anderson G.L., Limacher M., Assaf A.R., et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004;291:1701-1712.Anderson G.L., Limacher M., Assaf A.R., et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004;291:1701-1712.Chen W.Y., Manson J.E., Hankison S.E., et al. Unopposed estrogen therapy and the risk of invasive breast cancer. Arch Intern Med. 2006; 166: 1027-1032.Chen W.Y., Manson J.E., Hankison S.E., et al. Unopposed estrogen therapy and the risk of invasive breast cancer. Arch Intern Med. 2006; 166: 1027-1032.American Society for Reproductive Medicine. Estrogen and progestogen therapy in postmenopausal women. Fertil Steril. 2004; 82(suppl1): S70-S80.American Society for Reproductive Medicine. Estrogen and progestogen therapy in postmenopausal women. Fertil Steril. 2004; 82(suppl1): S70-S80.Nanda K., Bastian L.A., Hasselblad V., Simel D.L. Hormone replacement therapy and the risk of colorectal cancer: a meta-analysis. Obstet Gynecol. 1999; 93: 880-888.Nanda K., Bastian L.A., Hasselblad V., Simel D.L. Hormone replacement therapy and the risk of colorectal cancer: a meta-analysis. Obstet Gynecol. 1999; 93: 880-888.Anderson G.L., Limacher M., Assaf A.R., et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004;291:1701-1712.Anderson G.L., Limacher M., Assaf A.R., et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004;291:1701-1712.Hsia J., Langer R.D., Manson J.E., et al. Conjugated equine estrogens and coronary heart disease: The Women's Health Initiative. Arch Intern Med. 2006; 166: 357-365.Hsia J., Langer R.D., Manson J.E., et al. Conjugated equine estrogens and coronary heart disease: The Women's Health Initiative. Arch Intern Med. 2006; 166: 357-365.Kanaya A.M., Herrington D., Vittinghoff E. Glycemic Effects of Postmenopausal Hormone Therapy: The Heart and Estrogen/progestin Replacement Study: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Intern Med 2003 Volume 138 Number 16: 1-9.Kanaya A.M., Herrington D., Vittinghoff E. Glycemic Effects of Postmenopausal Hormone Therapy: The Heart and Estrogen/progestin Replacement Study: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Intern Med 2003 Volume 138 Number 16: 1-9.Espeland M.A., Hogan P.E., Fineberg S.E. Effect of postmenopausal hormone therapy on glucose and insulin concentrations. PEPI Investigators. Postmenopausal Estrogen/Progestin Interventions. Diabetes Care 1998 Oct; 21(10): 1589-95.Espeland M.A., Hogan P.E., Fineberg S.E. Effect of postmenopausal hormone therapy on glucose and insulin concentrations. PEPI Investigators. Postmenopausal Estrogen/Progestin Interventions. Diabetes Care 1998 Oct; 21(10): 1589-95.Kongnyuy E.J., Norman R.J., Flight I.H.K. Oestrogen and progestogen hormone replacement therapy for peri-menopausal and post-menopausal women: weight and body fat distribution Cochrane Database of Systematic Reviews 2007 Copyright © 2007 The Cochrane Collaboration.Kongnyuy E.J., Norman R.J., Flight I.H.K. Oestrogen and progestogen hormone replacement therapy for peri-menopausal and post-menopausal women: weight and body fat distribution Cochrane Database of Systematic Reviews 2007 Copyright © 2007 The Cochrane Collaboration.

The authors declare that there are no conflicts of interest present.