References

ometendo

Ожирение и метаболизм

Obesity and metabolism

2071-87132306-5524

Endocrinology Research Centre

10.14341/2071-8713-5297

ometendo-5297

Research Article

Статьи

Articles

Гормоны жировой ткани и их роль в нарушении репродуктивной функции у женщин с ожирением

Hormones of adipose tissue and their role in reproductive system dysfunction in obese women

Petunina

N A

napetunina@mail.ru

Makarov

I O

mosquite@mail.ru

Trukhina

L V

lvtruhina@gmail.com

Pchelintseva

N A

Kuzina

I A

mia986@mail.ru

2011

15122011

№4 (2011)

914

2011

Petunina N.A., Makarov I.O., Trukhina L.V., Pchelintseva N.A., Kuzina I.A.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.omet-endojournals.ru/jour/article/view/5297

В обзоре представлены данные литературы о физиологической и патофизиологической роли гормонов жировой ткани (адипонектина, фактора некроза опухолей-, интерлейкина-6, лептина, резистина, ингибитора активатора плазминогена-1). Рассмотрен вклад адипоцитокинов в развитие нарушений репродуктивной функции. Приведены результаты исследований о взаимосвязи ожирения и нарушений функции репродуктивной системы у женщин. Представлены данные зарубежной литературы о лекарственной терапии синдрома поликистозных яичников

The review presents data from the literature on the physiological and pathophysiological role of hormones of adipose tissue (adiponectin, tumor necrosis factor, interleukin-6, leptin, resistin, plasminogen activator inhibitor-1). The article considers the contribution of adipocytokines to the development of reproductive impairment. The results of studies on the relationship of the obesity and dysfunction of the reproductive system in women are presented.The review provides data from the literature about drug therapy of polycystic ovary syndrome.

ожирениеадипоцитокинырепродуктивная системасиндром поликистозных яичниковметформин

obesityadipocytokinesreproductive systempolycystic ovary syndromemetformin

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The authors declare that there are no conflicts of interest present.