ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/2071-8713-5296ometendo-5296Research ArticleСтатьиArticlesФизиология обмена кальция в почкахPhysiology of calcium metabolism in kidneysPigarovaE Akpigarova@gmail.com20111512201184№4 (2011)38Copyright © Pigarova E.A., 20112011Pigarova E.A.Pigarova E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/5296

Биологические функции кальция включают поддержание целостности скелета, передачу внутриклеточного сигнала, проницаемость клеток, сопряжение возбуждения-секреции и возбуждения-сокращения, а также оплодотворение клетки. Кальций в организме существует в различных формах: ионизированный, связанный с комплексами и связанный с белками, и только две первых формы могут проходить через мембраны клеток и фильтроваться почками. Данный обзор освещает физиологию, регуляцию и патогенез нарушений обмена кальция в почках.

Biologic functions of calcium include maintenance of skeletal integrity, signal transduction, cell permeability, excitation-secretion and excitation-contraction coupling and cell fertilization. There are various forms of calcium in the body: ionized, complexed and protein bound, and only two first forms can be filtered at the glomerulus and cross cell membranes. The present review covers the topics of physiology, regulation and pathogenesis of disturbances of renal calcium metabolism.

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The authors declare that there are no conflicts of interest present.