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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2071-8713-5274</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-5274</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Метаболический эффект гормона ростапри гипопитуитаризме у взрослых</article-title><trans-title-group xml:lang="en"><trans-title>Metabolicheskiy effekt gormona rostapri gipopituitarizme u vzroslykh</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Nagaeva</surname><given-names>E V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2010</year></pub-date><volume>7</volume><issue>1</issue><issue-title>№1 (2010)</issue-title><fpage>21</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Nagaeva E.V., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Nagaeva E.V.</copyright-holder><copyright-holder xml:lang="en">Nagaeva E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/5274">https://www.omet-endojournals.ru/jour/article/view/5274</self-uri><abstract><p>Обзор освещает основные метаболические нарушения, характерные для взрослых пациентов с гипопитуитаризмом
(ГП), которые зачастую невозможно решить с помощью традиционной заместительной гормональной терапии.
Положительное влияние терапии рекомбинантным гормоном роста (рГР) доказало необходимость ее применения у этих па-
циентов. Комплексное замещение всех тропных недостаточностей, включая соматотропный гормон (СТГ), позволяет орга-
низму работать в условиях гормонального обмена, максимально приближенного к нормальному, полностью нивелируя
или сводя к минимуму последствия метаболических нарушений, характерных для взрослых с ГП.</p></abstract><trans-abstract xml:lang="en"><p>Review coverts the basic metabolic disorders, characteristic for adult patients with hypopituitarism which frequently cannot be
solved by means of traditional replacement hormonal therapy. Positive influence of rGH therapy has proved necessity of its application
for these patients. Complex replacement of all pituitary deficiencies, including GH, allows an organism to work in the conditions of the
hormonal metabolism as much as possible similar to normal, completely leveling or reducing to a minimum of metabolic consequences
common for adults with hypopituitarism.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гипопитуитаризм</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>состав тела</kwd><kwd>инсулинорезистентность</kwd><kwd>гормон роста</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypopituitarism</kwd><kwd>cardiovascular diseases</kwd><kwd>body structure</kwd><kwd>insulin resistance</kwd><kwd>growth hormone</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Тюльпаков А.Н., Петеркова В.А. Соматотропная недостаточность. Москва, «ИндексПринт». 1998.</mixed-citation><mixed-citation xml:lang="en">Дедов И.И., Тюльпаков А.Н., Петеркова В.А. Соматотропная недостаточность. Москва, «ИндексПринт». 1998.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Amato G., Carella C., Fazio S. 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