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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2071-8713-5273</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-5273</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Влияние табакокурения на здоровье и массу телачеловека</article-title><trans-title-group xml:lang="en"><trans-title>Vliyanie tabakokureniya na zdorov'e i massu telacheloveka</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Mel'nichenko</surname><given-names>G A</given-names></name></name-alternatives><email xlink:type="simple">melnich@endocrincentr.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Butrova</surname><given-names>S A</given-names></name></name-alternatives><email xlink:type="simple">butrova42@mal.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Larina</surname><given-names>A A</given-names></name></name-alternatives><email xlink:type="simple">doc.larina@gmail.com</email></contrib></contrib-group><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2010</year></pub-date><volume>7</volume><issue>1</issue><issue-title>№1 (2010)</issue-title><fpage>15</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Mel'nichenko G.A., Butrova S.A., Larina A.A., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Mel'nichenko G.A., Butrova S.A., Larina A.A.</copyright-holder><copyright-holder xml:lang="en">Mel'nichenko G.A., Butrova S.A., Larina A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/5273">https://www.omet-endojournals.ru/jour/article/view/5273</self-uri><abstract><p>Табакокурение является причиной возникновения большого спектра заболеваний человека, а также его преждевре-
менной смерти. Отказ от курения несет неоспоримые преимущества для пациентов, однако сложен в связи с развивающейся
у них никотиновой зависимостью. Табачная зависимость в настоящее время расценивается как хроническое заболевание.
Рекомендации по лечению табачной зависимости, последнее переиздание которых относится к 2008 году, подчеркивают ог-
ромную опасность, которую несет никотиновая зависимость, регламентируют действия врача при работе с курильщиками,
рекомендуют использование эффективных методов лечения, включая психотерапию и лекарственные препараты. В настоящее
время доступны семь препаратов первой линии лечения табачной зависимости, значимо увеличивающих шансы успешного
отказа от курения, среди них пять препаратов никотинзаместительной терапии и два препарата, не содержащие никотин,
включая Варениклин. Особым фактором, снижающим приверженность пациентов к лечению, является умеренное увеличение
массы тела при отказе от курения. Боязнь набора веса является сильным мотивационным фактором продолжения курения,
особенно для женщин. В этом случае рекомендовано комплексное лечение пациентов, включающее психотерапию, рацио-
нальное питание, умеренные физические нагрузки.</p></abstract><trans-abstract xml:lang="en"><p>Tobacco smoking causes a lot of human deseases and is one of the main reasons of premature death. Smoking cessation is very
important for the patient's health but difficult for them due to development of nicotine dependence. Tobacco dependence is a chronic
disease. Smoking Cessation Clinical Practice Guideline, published in 2008, emphasize the dire health consequences of tobacco dependence,
regulate the way of treating patients who want to quit smoking, recommending the use of effective treatments, including counseling
and medications. Seven first-line medications (5 nicotine and 2 non-nicotine, including Varenicline) that reliably increase long-term
smoking abstinence rates are now available. Smoking cessation is accompanied by a moderate weigh gain. And its a strong motivational
factor to continue smoking, espcially for women. Сounseling, healthy food and physical activity are recommended for such patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>курение</kwd><kwd>Рекомендации по лечению табачной зависимости</kwd><kwd>Варениклин</kwd><kwd>набор массы тела</kwd></kwd-group><kwd-group xml:lang="en"><kwd>smoking</kwd><kwd>Smoking Cessation Clinical Practice Guideline</kwd><kwd>Varenicline</kwd><kwd>weigh gain</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Доказательная эндокринология: [руководство] /Под ред. Камачо П., Гариба Х., Сайзмора Г.; пер. с англ. под ред. Мельниченко Г.А., Рожинской Л.Я. - 2-е изд., испр. и доп. М.: ГЭОТАР-Медиа, 2009; 35-36.</mixed-citation><mixed-citation xml:lang="en">Доказательная эндокринология: [руководство] /Под ред. Камачо П., Гариба Х., Сайзмора Г.; пер. с англ. под ред. 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