ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/2071-8713-5224ometendo-5224Research ArticleСтатьиArticlesОжирение у молодых женщин - поиск эффективных методов коррекцииOzhirenie u molodykh zhenshchin - poisk effektivnykh metodov korrektsiiTkachevaO N-GalyautdinovaA Yu-20081512200854№4 (2008)3034Copyright © Tkacheva O.N., Galyautdinova A.Y., 20082008Tkacheva O.N., Galyautdinova A.Y.Tkacheva O.N., Galyautdinova A.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/5224ReferencesБалаболкин М.И. с соавт. Дифференциальная диагностика и лечение эндокринных заболеваний (руководство). М.: Медицина, 2002 год.Балаболкин М.И. с соавт. Дифференциальная диагностика и лечение эндокринных заболеваний (руководство). М.: Медицина, 2002 год.Европейская хартия по борьбе с ожирением. Европейская мимнистерская конференция ВОЗ по борьбе с ожирением. Стамбул, ноябрь, 2006 <http://www.euro.who.int/mediacentre/PR/2006/20061116>Европейская хартия по борьбе с ожирением. Европейская мимнистерская конференция ВОЗ по борьбе с ожирением. Стамбул, ноябрь, 2006 <http://www.euro.who.int/mediacentre/PR/2006/20061116>Шестакова М.В., Брескина О.Ю. Инсулинорезистентность: патофизиология, клинические проявления, подходы к лечению САХАРНЫЙ ДИАБЕТ Том 04 / N 10 / 2002Шестакова М.В., Брескина О.Ю. Инсулинорезистентность: патофизиология, клинические проявления, подходы к лечению САХАРНЫЙ ДИАБЕТ Том 04 / N 10 / 2002Aviles-Santa L., Sinding J., Raskin P. Effects of metformin in patients with poorly controlled insulin-treated type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1989; 131:182-188Aviles-Santa L., Sinding J., Raskin P. Effects of metformin in patients with poorly controlled insulin-treated type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1989; 131:182-188Borsika A. Rabin, Tegan K. Boehmer and Ross C. Brownson Cross-national comparison of environmental and policy correlates of obesity in Europe The European Journal of Public Health 2007 17(1): 53-61Borsika A. Rabin, Tegan K. Boehmer and Ross C. Brownson Cross-national comparison of environmental and policy correlates of obesity in Europe The European Journal of Public Health 2007 17(1): 53-61Campbell I.W., Howlett C.S. Worldwide experience of metformin as a glucose-lowering agent: a meta-analysis. Diabetes Metab Rev 11 (Suppl. 1): S57-S62, 1995Campbell I.W., Howlett C.S. Worldwide experience of metformin as a glucose-lowering agent: a meta-analysis. Diabetes Metab Rev 11 (Suppl. 1): S57-S62, 1995Charles M.A., Eschwege E., Grandmottet P. et al. Treatment with metformin of non non-diabetic men with hypertension, hypertrigliceridemia, and central fat distribution: the BIGPRO 1,2 trial. Diabetes Metab Res Rev 2000; 16: 2-7.Charles M.A., Eschwege E., Grandmottet P. et al. Treatment with metformin of non non-diabetic men with hypertension, hypertrigliceridemia, and central fat distribution: the BIGPRO 1,2 trial. Diabetes Metab Res Rev 2000; 16: 2-7.Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-the evidence report. National Institutes of Health. Obes Res. 1998; 2 (suppl 6): 51S-209S. Erratum in: Obes Res. 1998; 6: 464.Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-the evidence report. National Institutes of Health. Obes Res. 1998; 2 (suppl 6): 51S-209S. Erratum in: Obes Res. 1998; 6: 464.Fontbonne A., Charles M.A., Juhan-Vague I. The effect of metformin on the metabolic abnormalities associated with upper-body fat distribution. BIGPRO Study Group. Diabetes Care 1996; 19:920-926Fontbonne A., Charles M.A., Juhan-Vague I. The effect of metformin on the metabolic abnormalities associated with upper-body fat distribution. BIGPRO Study Group. Diabetes Care 1996; 19:920-926Freemark M., Bursey D. The Effects of Metformin on Body Mass Index and Glucose Tolerance in Obese Adolescents With Fasting Hyperinsulinemia and a Family History of Type 2 Diabetes Pediatrics, Apr 2001; 107: e55.Freemark M., Bursey D. The Effects of Metformin on Body Mass Index and Glucose Tolerance in Obese Adolescents With Fasting Hyperinsulinemia and a Family History of Type 2 Diabetes Pediatrics, Apr 2001; 107: e55.Gokcel A., Gumurdulu Y., Karakose H., Melek Ertorer E., Tanaci N., BascilTutuncu N., Guvener N. Evaluation of the safety and efficacy of sibutramine, orlistat and metformin in the treatment of obesity // Diabetes, Obesity and Metabolism; 2002; Vol. 4; Issue 1.Gokcel A., Gumurdulu Y., Karakose H., Melek Ertorer E., Tanaci N., BascilTutuncu N., Guvener N. Evaluation of the safety and efficacy of sibutramine, orlistat and metformin in the treatment of obesity // Diabetes, Obesity and Metabolism; 2002; Vol. 4; Issue 1.Guingliano D., De Rosa N., Di Maro G. еt al. Metformin improves glucose, lipid metabolism, and reduces blood pressure in hypertensive, obese women. Diabetes Care 1993; 16; 1387-90Guingliano D., De Rosa N., Di Maro G. еt al. Metformin improves glucose, lipid metabolism, and reduces blood pressure in hypertensive, obese women. Diabetes Care 1993; 16; 1387-90Kiess W., Siebler T., Englaro P., Leptin as a metabolic regulator during fetal and neonatal life and in childhood and adolescence. J Pediatr Endocrinol Metab 1998; 11:483-496Kiess W., Siebler T., Englaro P., Leptin as a metabolic regulator during fetal and neonatal life and in childhood and adolescence. J Pediatr Endocrinol Metab 1998; 11:483-496Knowler W.C., Barrett-Connor E., Fowler S.E., Hamman R.F., Lachin J.M., Walker E.A., Nathan D.M. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346: 393-403, 2002Knowler W.C., Barrett-Connor E., Fowler S.E., Hamman R.F., Lachin J.M., Walker E.A., Nathan D.M. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346: 393-403, 2002Lee A., Morley J. Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes. Obes Res 6:47-53, 1998Lee A., Morley J. Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes. Obes Res 6:47-53, 1998Morin-Papunen L.C., Koivunene R.M., Tomas C., Ruokonen A., Martikainene H.K. Decreased serum leptin concentrations during metformin therapy in obese women with polycystic ovary syndrome. J Clin Endocrinol Metab 1998; 83: 2566-2568Morin-Papunen L.C., Koivunene R.M., Tomas C., Ruokonen A., Martikainene H.K. Decreased serum leptin concentrations during metformin therapy in obese women with polycystic ovary syndrome. J Clin Endocrinol Metab 1998; 83: 2566-2568Obesity and overweight What are overweight and obesity? WHO Fact sheet N°311 September 2006 <http://www.who.int/mediacentre/factsheets/fs311/en/>Obesity and overweight What are overweight and obesity? WHO Fact sheet N°311 September 2006 <http://www.who.int/mediacentre/factsheets/fs311/en/>Paolisso G., Amatao L., Eccellente R., Effect of metformin on food intake in obese subjects. Eur J Clin Invest 1998; 28: 441-446Paolisso G., Amatao L., Eccellente R., Effect of metformin on food intake in obese subjects. Eur J Clin Invest 1998; 28: 441-446Paolisso G., Amato L., Eccellente R., Gambardella A., Tagliamonte M.R., Varricchio G., Carella C., Giugliano D., D'Onofrio F. Effect of metformin on food intake in obese subjects. Eur J Clin Invest 28: 441-446, 1998Paolisso G., Amato L., Eccellente R., Gambardella A., Tagliamonte M.R., Varricchio G., Carella C., Giugliano D., D'Onofrio F. Effect of metformin on food intake in obese subjects. Eur J Clin Invest 28: 441-446, 1998Report of the American Heart Association /National Heart, Lung, and Blood Institute / American Diabetes Association Conference on Scientific Issues Related to Management. Circulation 2004; 109: 551-556Report of the American Heart Association /National Heart, Lung, and Blood Institute / American Diabetes Association Conference on Scientific Issues Related to Management. Circulation 2004; 109: 551-556Riccio A., Del Prato S., de Kreutzenberg S.V., Tiengo A. Glucose and lipid metabolism in non-insulin dependent diabetes: effect of metformin. Diabetes Metab 1991; 17: 180-184Riccio A., Del Prato S., de Kreutzenberg S.V., Tiengo A. Glucose and lipid metabolism in non-insulin dependent diabetes: effect of metformin. Diabetes Metab 1991; 17: 180-184Rouru J., Hupponen R., Pesonen U., Koulu M. Subchronic treatment with metformin produces anorectic effect and reduces hyperinsulinemia in genetically obese Zucker rats. Life Sci 50: 1813-1820, 1992Rouru J., Hupponen R., Pesonen U., Koulu M. Subchronic treatment with metformin produces anorectic effect and reduces hyperinsulinemia in genetically obese Zucker rats. Life Sci 50: 1813-1820, 1992UK Prospective Diabetes Study 24 A six-year, randomized controlled trial comparing sulfonylurea, insulin and metformin therapy in patients with newly diagnosed type 2 diabetes that could not be controlled with diet therapy. Ann Intern Med 1998; 128: 165-175UK Prospective Diabetes Study 24 A six-year, randomized controlled trial comparing sulfonylurea, insulin and metformin therapy in patients with newly diagnosed type 2 diabetes that could not be controlled with diet therapy. Ann Intern Med 1998; 128: 165-175Velazquez E.M., Mendoza S., Hamer T., Sosa F., Glueck C.J. Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperan-drogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy. Metab Clin Exp 1994; 43: 647-654Velazquez E.M., Mendoza S., Hamer T., Sosa F., Glueck C.J. Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperan-drogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy. Metab Clin Exp 1994; 43: 647-654Williams D. Pregnancy: a stress test for life. Curr. Opin. Obstet. Gynecol. 2003; 15(6): 465-71.Williams D. Pregnancy: a stress test for life. Curr. Opin. Obstet. Gynecol. 2003; 15(6): 465-71.
The authors declare that there are no conflicts of interest present.