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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2071-8713-5205</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-5205</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Кардиоваскулярное «бремя» ожиренияи профилактические возможностиКсеникала (орлистат 120 мг)</article-title><trans-title-group xml:lang="en"><trans-title>Kardiovaskulyarnoe «bremya» ozhireniyai profilakticheskie vozmozhnostiKsenikala (orlistat 120 mg)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Bubnova</surname><given-names>M G</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2010</year></pub-date><volume>7</volume><issue>2</issue><issue-title>№2 (2010)</issue-title><fpage>22</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Bubnova M.G., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Bubnova M.G.</copyright-holder><copyright-holder xml:lang="en">Bubnova M.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/5205">https://www.omet-endojournals.ru/jour/article/view/5205</self-uri><abstract><p>Резюме. В статье обсуждаются проблемы ожирения и его вклад в сердечно-сосудистый и метаболические риски пациентов.
Отмечено увеличение распространенности ожирения в мире и России, обозначены патогенетические связи ожирения с рядом
кардиоваскулярных заболеваний и метаболических нарушений. Проанализированы современные подходы к снижению массы
тела. Рассмотрены протективные и профилактические возможности одного из наиболее эффективных и безопасных препаратов, предназначенных для снижения массы тела, - орлистата.
Resume. The obesity disease and concomitant cardiovascular and metabolic risk are discussed in this article. The prevalence of obesity
is increasing in Russia and worldwide with this we depict pathogenetic connections of obesity with cardiovascular disease and metabolic
disorders. The modern approaches to decrease the body weight are analysed in this article. The protective and prophylactic possibilities
of use of orlistat (Xenical), one of effective and safe drugs for decreasing body weight, are covered in this article.</p></abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>кардиометаболический риск</kwd><kwd>орлистат</kwd><kwd>Ксеникал</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>cardiometabolic risk</kwd><kwd>orlistat</kwd><kwd>Xenical</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бутрова С.А. Терапия ожирения: влияние Орлистата (Ксеникала) на кардиометаболические факторы риска // Ожирение и метаболизм 2008; 3(16): 1-4.</mixed-citation><mixed-citation xml:lang="en">Бутрова С.А. 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