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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2071-8713-5201</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-5201</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Сочетание улучшения контроля гликемии и снижения массы тела с минимальным риском гипогликемий - недостижимая цель вчера, реальность сегодня</article-title><trans-title-group xml:lang="en"><trans-title>Sochetanie uluchsheniya kontrolya glikemii i snizheniya massy tela s minimal'nym riskom gipoglikemiy - nedostizhimaya tsel' vchera, real'nost' segodnya</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Galstyan</surname><given-names>G R</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2011</year></pub-date><volume>8</volume><issue>1</issue><issue-title>№1 (2011)</issue-title><fpage>76</fpage><lpage>79</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Galstyan G.R., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Galstyan G.R.</copyright-holder><copyright-holder xml:lang="en">Galstyan G.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/5201">https://www.omet-endojournals.ru/jour/article/view/5201</self-uri><abstract/><trans-abstract xml:lang="en"/></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алгоритмы специализированной медицинской помощи больным сахарным диабетом. Издание четвертое. / Под ред. Акад. Дедова И.И. и проф. Шестаковой М.В. - М., 2009.</mixed-citation><mixed-citation xml:lang="en">Алгоритмы специализированной медицинской помощи больным сахарным диабетом. Издание четвертое. / Под ред. Акад. Дедова И.И. и проф. Шестаковой М.В. - М., 2009.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Шестакова М.В. Инкретины: новая веха в лечении сахарного диабета 2 типа. - М., 2010. - С. 62-69.</mixed-citation><mixed-citation xml:lang="en">Дедов И.И., Шестакова М.В. Инкретины: новая веха в лечении сахарного диабета 2 типа. - М., 2010. - С. 62-69.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Майоров А.Ю. Оценка эффективности обучения участковых терапевтов по программе управления сахарным диабетом 2 типа. Фарматека. - 2010. - № 16. - С. 87-95.</mixed-citation><mixed-citation xml:lang="en">Майоров А.Ю. Оценка эффективности обучения участковых терапевтов по программе управления сахарным диабетом 2 типа. Фарматека. - 2010. - № 16. - С. 87-95.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">American Heart Association, 2009. Available at http://www.americanheart.org/ downloadable/heart/ 1236204012112INTL.pdf.</mixed-citation><mixed-citation xml:lang="en">American Heart Association, 2009. Available at http://www.americanheart.org/ downloadable/heart/ 1236204012112INTL.pdf.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Cheung et al. Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006 // Am J Med. - 2009. - № 122. - Р. 443-53.</mixed-citation><mixed-citation xml:lang="en">Cheung et al. Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006 // Am J Med. - 2009. - № 122. - Р. 443-53.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Davis H.R., Mullins D.E. et al. Effect of chronic central administration of glucagonlike peptide-1 (7-36) amide on food consumption and body weight in normal and obese rats // Obes. Res. - 1998. - № 6. - Р. 147-156.</mixed-citation><mixed-citation xml:lang="en">Davis H.R., Mullins D.E. et al. Effect of chronic central administration of glucagonlike peptide-1 (7-36) amide on food consumption and body weight in normal and obese rats // Obes. Res. - 1998. - № 6. - Р. 147-156.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Diabetes Control and Complications Trial. DCCT Research Group // New. Eng.J.Med. - 1993. - № 329. - Р. 977-986.</mixed-citation><mixed-citation xml:lang="en">Diabetes Control and Complications Trial. DCCT Research Group // New. Eng.J.Med. - 1993. - № 329. - Р. 977-986.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Drucker D.J. The biology of incretin Hormones // Cell.Metab. - 2006. - № 3. - Р. 153-165.</mixed-citation><mixed-citation xml:lang="en">Drucker D.J. The biology of incretin Hormones // Cell.Metab. - 2006. - № 3. - Р. 153-165.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Finer N. et al. Liraglutide, a once-daily human GLP-1 analog, reverses incides of prediabetes in obese subjects: a randomized placebo-controlled 20-week trial // ADA. - 2009, poster number 1729.</mixed-citation><mixed-citation xml:lang="en">Finer N. et al. Liraglutide, a once-daily human GLP-1 analog, reverses incides of prediabetes in obese subjects: a randomized placebo-controlled 20-week trial // ADA. - 2009, poster number 1729.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Garber A. et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial // Lancet. - 2009. - № 373 (9662). - Р. 473-481.</mixed-citation><mixed-citation xml:lang="en">Garber A. et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial // Lancet. - 2009. - № 373 (9662). - Р. 473-481.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">IDF Diabetes Atlas (4th edition). - 2009. - № 26-27.</mixed-citation><mixed-citation xml:lang="en">IDF Diabetes Atlas (4th edition). - 2009. - № 26-27.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Jendle J., Nauck M.A. et al. Лираглутид, аналог человеческого ГПП-1 для введения один раз в день, снижает процентное содержание жира, висцеральной и подкожной жировой ткани. И печеночный стеатоз, в сравнении с глимепиридом, при назначении в дополнение к терапии метформином у пациентов с СД 2 типа //ADA. - 2008; oral presentation 106.</mixed-citation><mixed-citation xml:lang="en">Jendle J., Nauck M.A. et al. Лираглутид, аналог человеческого ГПП-1 для введения один раз в день, снижает процентное содержание жира, висцеральной и подкожной жировой ткани. И печеночный стеатоз, в сравнении с глимепиридом, при назначении в дополнение к терапии метформином у пациентов с СД 2 типа //ADA. - 2008; oral presentation 106.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kieffer T. et al. Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide-1 in vitro and in vivo by dipeptidil peptidase IV // Endocrinology. - 1995. - № 136. - Р. 3585-3596.</mixed-citation><mixed-citation xml:lang="en">Kieffer T. et al. Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide-1 in vitro and in vivo by dipeptidil peptidase IV // Endocrinology. - 1995. - № 136. - Р. 3585-3596.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kreymann B. et al. Glucagon-like peptide-17-36: a physiological incretin in man // Lancet. - 1987. - № 2. - Р. 1300-1304.</mixed-citation><mixed-citation xml:lang="en">Kreymann B. et al. Glucagon-like peptide-17-36: a physiological incretin in man // Lancet. - 1987. - № 2. - Р. 1300-1304.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Morrish et al. Mortality and causes of death in the WHO multinational study of vascular disease in diabetes // Diabetologia. - 2001. - № 44 (Suppl 2). - Р. S14-S21.</mixed-citation><mixed-citation xml:lang="en">Morrish et al. Mortality and causes of death in the WHO multinational study of vascular disease in diabetes // Diabetologia. - 2001. - № 44 (Suppl 2). - Р. S14-S21.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Rodbard H.W., Davidson J.A. Glycemic Control Algorithm, Statement by an American Association of Clinical Endocrinologists /American College of Endocrinology Consensus Panel on Type 2 Diabetes Mellitus: Аn Algorithm for Glycemic Control // Endocr Pract. - 2009. - № 15(6). - Р. 541.</mixed-citation><mixed-citation xml:lang="en">Rodbard H.W., Davidson J.A. Glycemic Control Algorithm, Statement by an American Association of Clinical Endocrinologists /American College of Endocrinology Consensus Panel on Type 2 Diabetes Mellitus: Аn Algorithm for Glycemic Control // Endocr Pract. - 2009. - № 15(6). - Р. 541.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Schjoldager B.T. et al. GLP-1 (glucagon-like peptide-1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans // Dig. Dis. Sci. - 1989. - № 34. - Р. 703-708.</mixed-citation><mixed-citation xml:lang="en">Schjoldager B.T. et al. GLP-1 (glucagon-like peptide-1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans // Dig. Dis. Sci. - 1989. - № 34. - Р. 703-708.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Standards of Medical Care in Diabetes-2009 // Diabetes Care. - 2009. - № 32 (spl. 1). - Р. S13-S61.</mixed-citation><mixed-citation xml:lang="en">Standards of Medical Care in Diabetes-2009 // Diabetes Care. - 2009. - № 32 (spl. 1). - Р. S13-S61.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Turton M.D. et al. A role for glucagon-like peptide-1 in the central regulation of feeding // Nature. - 1996. - № 379. - Р. 69-72.</mixed-citation><mixed-citation xml:lang="en">Turton M.D. et al. A role for glucagon-like peptide-1 in the central regulation of feeding // Nature. - 1996. - № 379. - Р. 69-72.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">UK Prospective Diabetes Study Group. Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) // Lancet. - 1998. -№ 52(9131). - Р. 837-853.</mixed-citation><mixed-citation xml:lang="en">UK Prospective Diabetes Study Group. Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) // Lancet. - 1998. -№ 52(9131). - Р. 837-853.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Willms E., Werner J. et al. Gastric empting, glucose responses and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7- 36) amide in type 2 (noninsulin-dependent) diabetic patients // J. Clin. Endocrinol. Metab. - 1996. -№ 81. - Р. 327-332.</mixed-citation><mixed-citation xml:lang="en">Willms E., Werner J. et al. Gastric empting, glucose responses and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7- 36) amide in type 2 (noninsulin-dependent) diabetic patients // J. Clin. Endocrinol. Metab. - 1996. -№ 81. - Р. 327-332.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
