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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2071-8713-5188</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-5188</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Сандостатин и Сандостатин ЛАР при метаболических, нейроэндокринных и онкологических заболеваниях</article-title><trans-title-group xml:lang="en"><trans-title>Sandostatin i Sandostatin LAR pri metabolicheskikh, neyroendokrinnykh i onkologicheskikh zabolevaniyakh</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пигарова</surname><given-names>Екатерина Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Pigarova</surname><given-names>E A</given-names></name></name-alternatives><email xlink:type="simple">kpigarova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дзеранова</surname><given-names>Лариса Константиновна</given-names></name><name name-style="western" xml:lang="en"><surname>Dzeranova</surname><given-names>L K</given-names></name></name-alternatives><email xlink:type="simple">metabol@endocrincentr.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="en" id="aff-1"><institution>&lt;p&gt;Endocrinology Research Centre, Moscow&lt;/p&gt;</institution><country>Russian Federation</country></aff><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>&lt;p&gt;Эндокринологический научный центр, Москва&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinology Research Centre, Moscow&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2011</year></pub-date><volume>8</volume><issue>1</issue><issue-title>№1 (2011)</issue-title><fpage>26</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пигарова Е.А., Дзеранова Л.К., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Пигарова Е.А., Дзеранова Л.К.</copyright-holder><copyright-holder xml:lang="en">Pigarova E.A., Dzeranova L.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/5188">https://www.omet-endojournals.ru/jour/article/view/5188</self-uri><abstract><p>Октреотид - это синтетический аналог гормона гипоталамуса соматостатина. Этот нейропепид широко распространен в органах человека и животных, как в ЦНС, так и на периферии, что определяет его потенциальные регуляторные функции. В 1987 году была получена первая регистрация препарата октреотида, препарат Сандостатин, для лечения акромегалии и карциноидных опухолей. В 1997 году появилась депо форма октреотида - Сандостатин ЛАР. В настоящее время препараты нашли свое применение во многих областях медицины при различных метаболических, нейроэндокринных и онкологических заболеваниях.</p></abstract><trans-abstract xml:lang="en"><p>Octreotide is a synthetic analog of hypothalamic hormone somatostatin. This neuropeptide is widely distributed in humans and animals in central nervous system and periphery, which defines its potential regulatory functions. In 1987 the first registration was received for octreotide preparation, Sandostatin, for treatment of acromegaly and carcinoid tumors. In 1997 a long lasting form of octreotide appeared - Sandostatin LAR. At the present time both preparations have found their use in multiple areas of medicine for treatment of different metabolic, neuroendocrine and oncologic diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>соматостатин</kwd><kwd>октреотид</kwd><kwd>Сандостатин</kwd><kwd>Сандостатин ЛАР</kwd><kwd>акромегалия</kwd><kwd>нейроэндокрин- ные опухоли</kwd><kwd>ожирение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>somatostatin</kwd><kwd>octreotide</kwd><kwd>Sandostatin</kwd><kwd>Sandostatin LAR</kwd><kwd>acromegaly</kwd><kwd>neuroendocrine tumors</kwd><kwd>obesity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">AACE Medical Guidelines for Clinical Practice for the diagnosis and treatment of acromegaly. 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