ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/2071-8713-5122ometendo-5122Research ArticleСтатьиArticlesПервичный идиопатический гиперальдостеронизм в клинической практикеPrimary idiopathic hyperaldosteronism in clinical practiceMolashenkoN Vmolashenko@mail.ruTroshinaE Atroshina@inbox.ru20121512201294№4 (2012)39Copyright © Molashenko N.V., Troshina E.A., 20122012Molashenko N.V., Troshina E.A.Molashenko N.V., Troshina E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/5122

Первичный гиперальдостеронизм (ПГА) – клинический синдром, развивающийся в результате избыточной продукции альдостерона клубочковой зоной коркового вещества надпочечников, при котором секреция альдостерона полностью или частично автономна по отношению к ренин-ангиотензиновой системе, что обусловливает развитие низкорениновой артериальной гипертензии (АГ). Первичный идиопатический гиперальдостеронизм (ПИГА) – один из вариантов в структуре синдрома ПГА. Частота ПИГА составляет, по различным оценкам, от 20 до 55% больных ПГА. Морфологическим субстратом ПИГА является двусторонняя мелко- или крупноузелковая гиперплазия надпочечников. В статье представлены современные данные о патогенезе, клинической картине, диагностике и лечении первичного идиопатического гиперальдостеронизма.

Primary hyperaldosteronism (PHA) is a clinical syndrome that develops as a result of excess production of aldosterone by adrenal glomerular zone, where aldosterone secretion is completely or partially autonomous in relation to the renin-angiotensin system. This factor leads to the development low renin arterial hypertension (AH). Primary idiopathic hyperaldosteronism is one of the forms of PHA. The prevalence of this form is variously estimated from 20 to 55% of patients with PHA. Morphological substrate primary idiopathic hyperaldosteronism is a bilateral micro- or macronodular adrenal hyperplasia. This article summarizes the contemporary view of the pathogenesis, clinical presentation, diagnosis and treatment of idiopathic hyperaldosteronism.

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The authors declare that there are no conflicts of interest present.